Plx1 is required for chromosomal DNA replication under stressful conditions
about
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repairTargeting DNA topoisomerase II in cancer chemotherapyPlk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell linesTimeless links replication termination to mitotic kinase activationDifferences in the DNA replication of unicellular eukaryotes and metazoans: known unknownsPreventing replication fork collapse to maintain genome integrityDbf4 regulates the Cdc5 Polo-like kinase through a distinct non-canonical binding interactionHpz1 modulates the G1-S transition in fission yeastSimultaneous in vitro characterisation of DNA deaminase function and associated DNA repair pathwaysProcessive DNA demethylation via DNA deaminase-induced lesion resolutionGEMC1 is a TopBP1-interacting protein required for chromosomal DNA replicationATR: an essential regulator of genome integrityMitotic crisis: the unmasking of a novel role for RPAThe role of the Fanconi anemia network in the response to DNA replication stress.ATR activation and replication fork restart are defective in FANCM-deficient cells.Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway.A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.Role of senescence and mitotic catastrophe in cancer therapy.BRCA2 coordinates the activities of cell-cycle kinases to promote genome stabilityPolo-like kinase 1 enhances survival and mutagenesis after genotoxic stress in normal cells through cell cycle checkpoint bypass.Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repairChk1 promotes replication fork progression by controlling replication initiation.Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint response.Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes.Replication licensing and the DNA damage checkpoint.Gene mutations and molecularly targeted therapies in acute myeloid leukemia.RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forksMolecularly targeted therapies in non-small-cell lung cancer annual update 2014Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease.Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stressTight Chk1 Levels Control Replication Cluster Activation in Xenopus.Polo-like kinase 1 (Plk1): an Unexpected Player in DNA Replication.Identification of rictor as a novel substrate of Polo-like kinase 1.ATR signalling: more than meeting at the fork.Replication initiation complex formation in the absence of nuclear function in Xenopus.Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation.Centrosomal protein FOR20 is essential for S-phase progression by recruiting Plk1 to centrosomes.Cell-free Xenopus egg extracts for studying DNA damage response pathways.Functional genomic screens identify CINP as a genome maintenance protein.
P2860
Q24316319-4A712782-E1AE-4E55-8512-8925C916C388Q24649711-F7DFB40A-046E-4122-B431-EC5612F8E803Q27334288-3BD90256-A8A2-4374-A17C-4F9C2838072FQ27342850-344FC0C6-A033-485B-B637-EC2782D6BA44Q27694684-E8E254E3-69A1-485C-9409-8C5D3FAB8216Q28083804-3D31CC94-5598-4AFF-A842-BA989FAE4A13Q28476633-F37B89B0-54E7-45EF-B3A3-5D1E7D912A16Q28483624-40B4E612-7A6F-4709-AC23-221643C4EF70Q28536559-32CAE97D-6806-421B-BAB5-131679728BDEQ28540726-DA064416-212D-446B-9F0E-724516A3AA4AQ28590548-E54231B3-1993-47DE-A4BB-EF5280094B0EQ29547883-EE1CCEC5-CD84-45AC-899B-B274D3A1E1BFQ30857441-670BA7EA-1864-4B1F-9131-3266C035494BQ33347783-461F4CB2-5CB8-410D-B86E-CD4C0D2D5110Q33522555-A077481C-9FDF-445D-8BDF-8AC07D54307EQ33526233-424C16C4-41A9-4077-842B-4958870E565DQ33552180-43FD1C05-7E95-4814-A192-9F3BF75811CCQ33683160-526C2840-0E26-4E7F-8550-214B19269426Q33775659-51FC641E-54BA-4EC2-BD8A-E37AB314E388Q33829178-2D17874A-6C8A-4935-9676-04E79016F432Q34011429-70D8504D-CF17-4B27-A14C-0B30384F8002Q34136566-DCC47986-11BC-4020-B204-F61F2417AD0CQ34218130-A765D0EE-3703-4B58-AF0C-B68537433A17Q34313126-7CE3E526-78D7-4F05-93EB-FC5595C51F82Q34354173-B639BB19-9DA0-4552-8812-EBC0E986E5B6Q34547673-7E9A44FA-3DBA-4DDF-A958-A7FF1429D45AQ34647741-FF468BA8-A991-4919-9236-64647D6589AEQ35011618-D8A6A2D0-22A8-424C-93FC-40D287B084A0Q35136424-CE043CE8-78A2-455E-8FA2-8E6AE78881BAQ35582357-CA9FC428-60BB-4AFB-ABDD-D6D070C93992Q35598813-CBD7FFA6-595F-436A-A00F-71C0A3CB5570Q35653663-E14393A6-6FFA-45E2-8146-4E5BF50456A7Q35984222-69639AAD-90EC-4FBC-99CF-E3C8B9177C6FQ36189356-9A9333CC-1056-42A1-8A3C-2AB5C67DE011Q36918246-FA3746E4-2CF2-4774-B8B2-89F41D032956Q37169815-BC27FFC0-6078-4408-B7B2-62744F081309Q37192073-363C1DA6-E3A3-428A-8CFC-8E33E70D774EQ37279858-342E6F72-83E6-4F14-8FB2-7A41AC9B12F1Q37351727-BA81A94A-D265-469D-908B-4B3A795F9723Q37428971-B61F7FB3-1FF5-4980-A70E-EA10305150A5
P2860
Plx1 is required for chromosomal DNA replication under stressful conditions
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Plx1 is required for chromosomal DNA replication under stressful conditions
@ast
Plx1 is required for chromosomal DNA replication under stressful conditions
@en
type
label
Plx1 is required for chromosomal DNA replication under stressful conditions
@ast
Plx1 is required for chromosomal DNA replication under stressful conditions
@en
prefLabel
Plx1 is required for chromosomal DNA replication under stressful conditions
@ast
Plx1 is required for chromosomal DNA replication under stressful conditions
@en
P2860
P356
P1433
P1476
Plx1 is required for chromosomal DNA replication under stressful conditions
@en
P2093
Alessia Errico
Kristina Trenz
P2860
P304
P356
10.1038/EMBOJ.2008.29
P407
P577
2008-02-28T00:00:00Z