Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7
about
A Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration.Functional regulation of semaphorin receptors by proprotein convertasesThe secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesisSubtilisin-like proprotein convertase expression, localization, and activity in the human retina and optic nerve headHPV16 infection of HaCaTs is dependent on β4 integrin, and α6 integrin processing.Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasisHuman mannose 6-phosphate-uncovering enzyme is synthesized as a proenzyme that is activated by the endoprotease furin.Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus.Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouseProprotein convertases in tumor progression and malignancy: novel targets in cancer therapy.Embryo implantation is closely associated with dynamic expression of proprotein convertase 5/6 in the rabbit uterus.Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model.Transgenic overexpression of the proprotein convertase furin enhances skin tumor growthGain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome.Enhanced UV-induced skin carcinogenesis in transgenic mice overexpressing proprotein convertases.Proprotein convertases play an important role in regulating PKGI endoproteolytic cleavage and nuclear transport.A role for pericytes as microenvironmental regulators of human skin tissue regeneration.The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model.The proprotein convertase furin in tumour progression.Renal-skin syndromes.The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.The endoproteolytic processing of alphavbeta5 integrin is involved in cytoskeleton remodelling and cell migration.Substrate cleavage analysis of furin and related proprotein convertases. A comparative study.Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme.Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage.Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions.The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1.Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.
P2860
Q27316820-01F732E1-B6FC-4844-9B83-EB27C21EB9FFQ28203827-2E15A1FB-1EFD-422E-BC3B-AC6DFF6CEC16Q28208308-6EFA4995-BE57-4DE7-8B47-C5E693B31929Q28240099-9C16FD46-33DE-413E-A444-3CD19AA2AA8EQ33714325-BE0E813C-16D5-4857-B61D-1855D08C3282Q34009826-1B4253C5-0579-4732-B466-13B7FB3F1F75Q34132809-770FF14F-8BA2-4303-9164-070E54831E31Q34219410-8008E620-4422-4741-A9FB-B1AF0DA338CBQ34233493-2B6A87FE-3157-4E85-ABAE-74A685CB81D4Q34679398-EB330C85-2258-4798-8CEC-EBF31B62D43CQ34817755-82F09EB0-9495-4C35-BDD7-4E155AE1BEFBQ35098301-1F1BC0CB-19DA-4634-B228-AE8A8159DE92Q35949753-CB4E04CE-53A2-4471-AEDD-BBF8D3E48FB6Q36498046-68DFBB4E-493C-4659-9DB4-F2C832BC2715Q36629417-ABC62D68-AA88-45FC-9285-64E7AF4B3E84Q37054485-2C766215-B849-4EED-9280-E31A0B98B5B9Q37328427-AF4EFC10-A780-4203-AD93-7718C4FA7E8CQ37351878-3AB48C44-7AC7-4A90-A6AD-2508F82D50C6Q39215671-84D19622-C613-4BED-B126-2E36F1164799Q39255689-0C54FB61-28C0-4381-AB28-0A2009FC265BQ40379230-D35FCEC4-1E97-4D1D-87A0-2A37B3426245Q40596217-07206EE6-A30B-4FED-8578-252EB985024FQ40643084-3475F5AA-3E8F-4980-B05E-A88B7BC8194DQ40834313-71EE4344-09CF-40DA-821B-95E99C267C5CQ43002977-7D7FB652-659C-4B53-A392-C6DC66B8E6B8Q43636939-33E3AB5D-D696-47C2-BAED-52D7624D6B75Q44279243-A3922D4E-9955-4935-AC9C-A2028416E6DCQ45073569-6CD4FE11-3C10-4510-A512-7E36CEF596BB
P2860
Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7
description
2000 nî lūn-bûn
@nan
2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@ast
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@en
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@en-gb
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@nl
type
label
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@ast
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@en
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@en-gb
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@nl
prefLabel
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@ast
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@en
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@en-gb
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@nl
P2093
P2860
P356
P1433
P1476
Endoproteolytic processing of ...... g enzyme (PACE) 4, PC5B or PC7
@en
P2093
J C Lissitzky
J Marvaldi
J S Munzer
M Chrétien
N G Seidah
S Benjannet
P2860
P356
10.1042/BJ3460133
P407
P478
P577
2000-02-15T00:00:00Z