A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage - Wikidata - awgldk - TriplyDB

A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage

A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage

http://www.wikidata.org/entity/Q24651421

about

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9 Chk2 activation dependence on Nbs1 after DNA damage Highlight: BRCA1 and BRCA2 proteins in breast cancer PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2 Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379 Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1 hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2 Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53 Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks.Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01 Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex Role of PML and the PML-nuclear body in the control of programmed cell death Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase Blocking Chk1 expression induces apoptosis and abrogates the G2 checkpoint mechanism Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition The Schizosaccharomyces pombe checkpoint kinases Chk1 and Cds1 are important for cell survival in response to cisplatin Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks Xenopus Cds1 is regulated by DNA-dependent protein kinase and ATR during the cell cycle checkpoint response to double-stranded DNA ends DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach.

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P2860

A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage

http://www.wikidata.org/entity/Q24651421

description

1999 nî lūn-bûn

@nan

1999 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի մարտին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

A human Cds1-related kinase th ...... ellular response to DNA damage

@ast

A human Cds1-related kinase th ...... ellular response to DNA damage

@en

A human Cds1-related kinase th ...... ellular response to DNA damage

@nl

type

label

A human Cds1-related kinase th ...... ellular response to DNA damage

@ast

A human Cds1-related kinase th ...... ellular response to DNA damage

@en

A human Cds1-related kinase th ...... ellular response to DNA damage

@nl

prefLabel

A human Cds1-related kinase th ...... ellular response to DNA damage

@ast

A human Cds1-related kinase th ...... ellular response to DNA damage

@en

A human Cds1-related kinase th ...... ellular response to DNA damage

@nl

P1433

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

A human Cds1-related kinase th ...... ellular response to DNA damage

@en

P2093

A L Brown

http://www.w3.org/2001/XMLSchema#string

C H Lee

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H Piwnica-Worms

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J H Chung

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J K Schwarz

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N Mitiku

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P2860

Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

The Schizosaccharomyces pombe rad3 checkpoint gene

cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

Molecular interaction between the Strep-tag affinity peptide and its cognate target, streptavidin

TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint.

P304

3745-50

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scholarly article

P356

10.1073/PNAS.96.7.3745

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P433

7

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P478

96

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1999-03-30T00:00:00Z

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13194310

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P698

10097108

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P921

P932

22365

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