p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis - Wikidata - awgldk - TriplyDB

p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

http://www.wikidata.org/entity/Q24682554

about

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids Raf family kinases: old dogs have learned new tricks Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling Redundancy in the World of MAP Kinases: All for One Chronic infection by Leishmania amazonensis mediated through MAPK ERK mechanisms Endosome maturation Functional deregulation of KIT: link to mast cell proliferative diseases and other neoplasms EGF receptor trafficking: consequences for signaling and cancer Regulation of mTORC1 by amino acids Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.Endocytosis and signalling: intertwining molecular networks Epidermal growth factor stimulates extracellular-signal regulated kinase phosphorylation of a novel site on cytoplasmic Dynein intermediate chain 2 Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis.The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons.A-RAF kinase functions in ARF6 regulated endocytic membrane traffic.RagA, but not RagB, is essential for embryonic development and adult mice.An inside view: VEGF receptor trafficking and signaling AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve Comprehensive proteomic and transcriptomic characterization of hepatic expression signatures affected in p14 liver conditional knockout mice.Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor.Loss of PiT-1 results in abnormal endocytosis in the yolk sac visceral endoderm LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk Ubiquitination regulates the internalization, endolysosomal sorting, and signaling of the erythropoietin receptor p38 signaling and receptor recycling events in a microfluidic endothelial cell adhesion assay.The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.Drosophila Vps4 promotes Epidermal growth factor receptor signaling independently of its role in receptor degradation.A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.Slit-Dependent Endocytic Trafficking of the Robo Receptor Is Required for Son of Sevenless Recruitment and Midline Axon Repulsion Phytophthora infestans RXLR-WY Effector AVR3a Associates with Dynamin-Related Protein 2 Required for Endocytosis of the Plant Pattern Recognition Receptor FLS2.Multi-Compartmentalisation in the MAPK Signalling Pathway Contributes to the Emergence of Oscillatory Behaviour and to Ultrasensitivity.The scaffold protein MEK Partner 1 is required for the survival of estrogen receptor positive breast cancer cells Late endosomal traffic of the epidermal growth factor receptor ensures spatial and temporal fidelity of mitogen-activated protein kinase signaling

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P2860

p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

http://www.wikidata.org/entity/Q24682554

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

@ast

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

@en

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

@nl

type

label

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

@ast

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

@en

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

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prefLabel

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

@ast

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

@en

p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

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Journal of Cell Biology

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p14-MP1-MEK1 signaling regulat ...... tion during tissue homeostasis

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P2093

Andreas Villunger

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Christoph Klein

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Diana Hilber

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Georg Bohn

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Mariana E de Araujo

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Martin Offterdinger

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Miriam Erlacher

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Nicole Taub

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Robert Kurzbauer

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Stephan Geley

http://www.w3.org/2001/XMLSchema#string

P2860

KSR, a novel protein kinase required for RAS signal transduction

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes

A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment

Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin

ERK and beyond: insights from B-Raf and Raf-1 conditional knockouts

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

Signaling via mitogen-activated protein kinase kinase (MEK1) is required for Golgi fragmentation during mitosis

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861-868

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485550

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10.1083/JCB.200607025

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6

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175

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Lukas Alfons Huber

Michael W. Hess

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6621140

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17178906

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