Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
about
Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivoA crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domainsKindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrinsInteraction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1Association of Grb7 with phosphoinositides and its role in the regulation of cell migrationNon-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interactionAn alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signalingIQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain foldStructural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factorsThe type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membraneExo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificityThe Phox homology (PX) domain, a new player in phosphoinositide signallingARF-GEP(100), a guanine nucleotide-exchange protein for ADP-ribosylation factor 6Therapeutic Implications of Targeting AKT Signaling in MelanomaTargeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria.FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane rufflesSWAP-70 identifies a transitional subset of actin filaments in motile cells.A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and functionTurning off AKT: PHLPP as a drug targetPhosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells.The Caenorhabditis elegans Kinesin-3 motor UNC-104/KIF1A is degraded upon loss of specific binding to cargoComputational studies of the binding profile of phosphoinositide PtdIns (3,4,5) P₃ with the pleckstrin homology domain of an oomycete cellulose synthaseCrystal structures of the Dab homology domains of mouse disabled 1 and 2Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational changeStructural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphateStructural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange FactorsStructural and mechanistic insights into the association of PKC -C2 domain to PtdIns(4,5)P2Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14Structure-function study of the N-terminal domain of exocyst subunit Sec3Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) DomainIntracellular phosphatidylserine is essential for retrograde membrane traffic through endosomesStructural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorStructural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica PathogenesisStructural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2Structures of the pleckstrin homology domain ofSaccharomyces cerevisiaeAvo1 and its human orthologue Sin1, an essential subunit of TOR complex 2Structural Analyses of the Slm1-PH Domain Demonstrate Ligand Binding in the Non-Canonical Site
P2860
Q24292193-B0BEC6E1-9837-48AB-BC54-F8311357D194Q24292431-E29DB6F6-AD9A-4505-9CEF-585745A44878Q24292965-D07F776F-F089-454F-8750-04A4A1D37C43Q24293222-E50A96BB-28C0-44F7-AC87-7A6EA90FB48AQ24296214-8A31C1D1-1704-4E6C-BFFD-B3B2AA7A09D4Q24297860-373DF37E-F65D-4091-A0BD-2C79D6443E2FQ24299126-D34572BD-9E04-4A81-A5AB-A1C4CD1AA7F3Q24307993-CE330E88-B157-4370-A1FE-05804E260A9DQ24310171-3A69C349-93B3-4CDD-8DC4-C48AF5FEE9B6Q24312786-45529317-8E24-40D4-BA20-EB80AA313DCAQ24317300-21C65F7C-49CB-4A6D-977F-92D5354906C1Q24523405-1917EC34-5081-423F-B139-C98AF522E496Q24529568-0C7FE4A9-EDA4-4AF5-BE52-8EC091986FDAQ24533405-05CE94CC-24B9-4578-9300-6BDDA83EE494Q24533547-874AD4D6-86F5-43E4-B50A-65521E46F844Q24605526-78B60EB8-376E-4927-BF19-EB5B3A025383Q24631438-6615B1A7-E28A-4F01-B5DF-3868F120436CQ24644997-3F4A250A-E264-412A-9F24-631A678E6EF1Q24652635-382D54ED-232C-4325-9B62-A24033DDAE23Q24682569-FDBACBDC-A827-46DA-A4B4-400DC125E1F2Q24684919-A35D6FEF-4716-487A-A03C-59412DC112B6Q27014094-FB26F8A7-646B-44A8-94D9-12FDE1BFA4E7Q27342410-E5AAF55E-8FD6-42C4-9D07-2CDEF1CD2224Q27345244-149BC932-785C-44EC-BD9E-C9229C534849Q27350315-552485B7-C620-41A0-A8AD-FF203835F6EBQ27641511-77F00420-A3BF-45FC-A5BB-CC2B4855BDCAQ27642001-AF844EBC-1806-40C2-8F4B-B0F6D97CBA1CQ27649130-7F96B13C-535B-48AD-A700-BC22DD30F950Q27649147-DB61EBB4-E90E-43FB-97AE-4DFD4F179416Q27654558-476DDD6F-AED1-4782-B297-66473660222BQ27656836-E242958E-79D6-460D-8F48-FF2186E36E4AQ27659629-5FEA24D3-3BC4-4935-8DA0-EB5E43A3C481Q27659933-A57D094E-EF5F-43CF-A17A-31CFB10D7225Q27667394-2C49EE8F-7F0A-46D0-B27B-C8C86DCEFD10Q27673759-7968EF3A-8667-4D67-8305-CFF85FC09A85Q27674679-755DE683-57EB-4FD6-91B3-3DFAB5934C24Q27675572-CD3FFC1A-6F20-4387-BC5A-2FF497F37B2BQ27676119-32002658-DD78-4506-A192-31CF943904ADQ27678534-99333765-9AE6-4215-A156-5E91BE1EDBEDQ27679006-A9BEB609-942A-4993-9EF0-AB76F5956942
P2860
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@ast
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@en
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@nl
type
label
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@ast
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@en
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@nl
prefLabel
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@ast
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@en
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@nl
P2093
P3181
P1433
P1476
Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains
@en
P2093
E Fournier
E Y Skolnik
J M Kavran
K M Ferguson
S J Isakoff
V G Sankaran
P304
P3181
P356
10.1016/S1097-2765(00)00037-X
P577
2000-08-01T00:00:00Z