Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1
about
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium.Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide ScaffoldDevelopment of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoesNeospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapyBiochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active CompoundsBumped kinase inhibitor 1294 treats established Toxoplasma gondii infection.Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondiiTheileria equi isolates vary in susceptibility to imidocarb dipropionate but demonstrate uniform in vitro susceptibility to a bumped kinase inhibitorThe gatekeeper residue and beyond: homologous calcium-dependent protein kinases as drug development targets for veterinarian Apicomplexa parasites.Three-dimensional structures in the design of therapeutics targeting parasitic protozoa: reflections on the past, present and future.Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activityIn Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninumBenzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1.SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1.Bumped kinase inhibitor prohibits egression in Babesia bovisA novel calcium-dependent protein kinase inhibitor as a lead compound for treating cryptosporidiosis.Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1.Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity.Drugs in development for toxoplasmosis: advances, challenges, and current status.Screening for small molecule inhibitors of Toxoplasma gondii.Protein kinases of Toxoplasma gondii: functions and drug targets.Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.Inhibition of Calcium-Dependent Protein Kinase 1 (CDPK1) In Vitro by Pyrazolopyrimidine Derivatives Does Not Correlate with Sensitivity of Cryptosporidium parvum Growth in Cell Culture.Drug target identification in protozoan parasites.Extended-spectrum antiprotozoal bumped kinase inhibitors: A review.Inhibition of Calcium Dependent Protein Kinase 1 (CDPK1) by Pyrazolopyrimidine Analogs Decreases Establishment and Reoccurrence of Central Nervous System Disease by Toxoplasma gondii.In vitro growth inhibition of Theileria equi by bumped kinase inhibitors.A critical evaluation of pyrrolo[2,3-d]pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors
P2860
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P2860
Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@ast
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@en
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@nl
type
label
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@ast
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@en
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@nl
prefLabel
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@ast
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@en
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@nl
P2093
P2860
P356
P1476
Multiple Determinants for Sele ...... Dependent Protein Kinase CDPK1
@en
P2093
Anna M W Fox
B Gayani K Perera
Christophe L M J Verlinde
David J Leibly
Dustin J Maly
Edward J Dale
Eric T Larson
Erkang Fan
Ethan A Merritt
P2860
P304
P356
10.1021/JM201725V
P407
P577
2012-03-22T00:00:00Z