Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism. - Wikidata - awgldk - TriplyDB

Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.

Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.

http://www.wikidata.org/entity/Q27934623

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Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex K11-linked ubiquitin chains as novel regulators of cell division The Renaissance or the cuckoo clock Atomic structure of the APC/C and its mechanism of protein ubiquitination.Insights into anaphase promoting complex TPR subdomain assembly from a CDC26–APC6 structure The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27 Structural analysis of human Cdc20 supports multisite degron recognition by APC/C The Four Canonical TPR Subunits of Human APC/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a TPR Suprahelix The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.Ama1p-activated anaphase-promoting complex regulates the destruction of Cdc20p during meiosis II.Spatiotemporal regulation of the anaphase-promoting complex in mitosis The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.Molecular architecture and mechanism of the anaphase-promoting complex Activation of the APC/C ubiquitin ligase by enhanced E2 efficiency APC-targeted RAA1 degradation mediates the cell cycle and root development in plants Anaphase-promoting complex/cyclosome protein Cdc27 is a target for curcumin-induced cell cycle arrest and apoptosis.The biochemistry of mitosis Meiotic control of the APC/C: similarities & differences from mitosis.Protein-linked ubiquitin chain structure restricts activity of deubiquitinating enzymes.An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C Ubiquitination of Cdc20 by the APC occurs through an intramolecular mechanism Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation Design principles of a universal protein degradation machine.State of the APC/C: organization, function, and structure.biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes.Mechanism of APC/CCDC20 activation by mitotic phosphorylation.A Wee1 checkpoint inhibits anaphase onset.Mutually dependent degradation of Ama1p and Cdc20p terminates APC/C ubiquitin ligase activity at the completion of meiotic development in yeast.Mechanisms of ubiquitin transfer by the anaphase-promoting complex.Structure, function and mechanism of the anaphase promoting complex (APC/C).Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy.Structural insights into anaphase-promoting complex function and mechanism.Panta rhei: the APC/C at steady state.Understanding the structural basis for controlling chromosome division.APC/CFzr/Cdh1-Dependent Regulation of Planar Cell Polarity Establishment via Nek2 Kinase Acting on Dishevelled.Structural basis for the subunit assembly of the anaphase-promoting complex.

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P2860

Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.

http://www.wikidata.org/entity/Q27934623

description

2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... e substrate-binding mechanism.

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Analysis of activator-binding ...... ve substrate-binding mechanism

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Mary E Matyskiela

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P2860

Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C

Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

An architectural map of the anaphase-promoting complex

Sequence variation in ligand binding sites in proteins

Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine

Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5

Design of stable alpha-helical arrays from an idealized TPR motif

Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

A novel destruction sequence targets the meiotic regulator Spo13 for anaphase-promoting complex-dependent degradation in anaphase I.

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10.1016/J.MOLCEL.2009.02.027

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