Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features. - Wikidata - awgldk - TriplyDB

Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.

Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.

http://www.wikidata.org/entity/Q34062498

about

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state NRF2, a Key Regulator of Antioxidants with Two Faces towards Cancer Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance The mutational landscape of hepatocellular carcinoma Hydrogen peroxide - production, fate and role in redox signaling of tumor cells Nrf2 and Notch Signaling in Lung Cancer: Near the Crossroad Emerging roles of Nrf2 signal in non-small cell lung cancer Drugging the addict: non-oncogene addiction as a target for cancer therapy Epigenetic regulation of Keap1-Nrf2 signaling Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development The complexity of the Nrf2 pathway: beyond the antioxidant response The Keap1-Nrf2 system in cancers: stress response and anabolic metabolism Cytoprotection "gone astray": Nrf2 and its role in cancer A new model for raf kinase inhibitory protein induced chemotherapeutic resistance Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer CDDO-Me protects normal lung and breast epithelial cells but not cancer cells from radiation Genetic disruption of KEAP1/CUL3 E3 ubiquitin ligase complex components is a key mechanism of NF-kappaB pathway activation in lung cancer.Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification--mass spectrometry data.A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells.Molecular pathways and therapeutic targets in lung cancer Genomics of squamous cell lung cancer Methylation of the KEAP1 gene promoter region in human colorectal cancer NRF2 and cancer: the good, the bad and the importance of context.Genetic polymorphism in the NRF2 gene as a prognosis marker for cancer chemotherapy.A genetic basis for the variation in the vulnerability of cancer to DNA damage.Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism.The PTEN/NRF2 axis promotes human carcinogenesis Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes SNP (-617C>A) in ARE-like loci of the NRF2 gene: a new biomarker for prognosis of lung adenocarcinoma in Japanese non-smoking women.Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer Unraveling the molecular genetics of head and neck cancer through genome-wide approaches Clinical significance of Keap1 and Nrf2 in oral squamous cell carcinoma.Dual roles of NRF2 in tumor prevention and progression: possible implications in cancer treatment Cancer-risk module identification and module-based disease risk evaluation: a case study on lung cancer.NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage.Keap1 expression has independent prognostic value in pancreatic adenocarcinomas Expression of p63 and CK5/6 in early-stage lung squamous cell carcinoma is not only an early diagnostic indicator but also correlates with a good prognosis.KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma.Functional Role of NRF2 in Cervical Carcinogenesis.

P2860

Q26741668-FE2912F3-4E6E-4C01-B46A-496B9CBCA9C8 Q26747249-D19A9FA1-ABC6-4D15-B917-764FE15EDC57 Q26747274-2549750A-8B0A-4EC3-B6AE-6BB51C95F001 Q26774916-10554BCF-01F7-4FE6-889B-F61D9D4AF484 Q26777478-4FEEE2B7-1742-4CA3-A810-D0E1CBCCB94D Q26787065-3AD3FFF2-A219-444D-8199-A97BCABA9954 Q28066915-1C01CBF2-7274-453A-83D3-0811F46A5D9A Q28078928-E11D48C4-FF66-45FF-BB40-B305FB9FA638 Q28079559-E8B0713A-E236-406D-AC37-8D12376E9C36 Q28084220-E4A2640F-B194-4B3A-85F7-00C517C29345 Q28384678-306BD5E3-3921-445D-AEED-2632C8DCEF29 Q28389296-D12FB153-C08B-4C1F-A5C9-950CF27337B6 Q28392347-69F4849B-EBD8-45A5-A7A2-1AD8BAB40D0F Q28393784-89565968-4E9E-4E91-A716-EA5D94CC4D71 Q28478945-B2D8FCEA-B57D-4528-9FE2-BA4FF02B5381 Q28505734-9B193C68-41FD-43E9-8F8A-C29681A8C5D4 Q28542835-F4B9795D-3460-415D-BE59-713A02BF8006 Q30503861-D816DE1E-5D32-4666-BC5A-D5E9FAFECF33 Q30858730-41D34082-87F4-4DC8-B255-89700E6A431F Q33623634-E19DB9F1-7557-4C96-8CD7-5BAAEB341A74 Q33688872-FEF0F2B9-87C7-4A15-89EC-E6EA75752268 Q33777454-8958838B-72E2-4D27-99BB-773D06490A5C Q34156322-08B11564-9CCE-4974-9463-93EAE200F1A8 Q34289003-D429157F-9117-41A6-9785-EAF6632DBE78 Q34448767-658FBA38-1DCB-42B8-B53C-63D44C3341D5 Q34523304-A64B6F09-5F42-4A2E-8F73-20A0D2F18067 Q34534013-B5F22D01-87B7-45A3-9B46-683D13FA93E6 Q34579435-26B759D2-BF62-4B26-B4F5-151E3DB6F3CF Q34667055-20186DD1-A535-4776-BE4E-E6E36ABB6C58 Q34989327-C1E96600-35B3-4745-A22E-CF55725D5EAD Q34996337-BF7416CD-24CA-4FCE-B075-9064955E6A01 Q35025009-A3725D62-3BAC-4E2A-9D21-8E79165F6EF8 Q35080411-987F4279-E337-42AD-BF75-1F7FF8F034B2 Q35118710-D7C8B8D4-9A62-4FCF-96E8-9F1B3EBFF159 Q35124393-40A21E15-C965-4966-A8A1-4B40DEDD4903 Q35408649-43D7281D-338A-4DBE-818E-F6C244DCCF0E Q35576302-10509CDB-6360-4702-8E10-AF9422423B00 Q35663394-6BBC5B24-658C-4723-AC53-BD75182CFB7E Q35711633-45643087-D404-4FD8-A112-F7B354DD0BFC Q35738532-BDB1DC39-C853-4289-8E6C-A4FF096FEB2B

P2860

Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.

http://www.wikidata.org/entity/Q34062498

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@ast

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@en

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@nl

type

label

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@ast

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@en

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@nl

prefLabel

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@ast

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@en

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@nl

P1433

Q34062498-6EC3B1AA-81C9-4FAC-B973-78DDE5B77815

P1476

Q34062498-FE6C29EE-B981-47BD-8D3A-FAE44CA8C3D5

P2093

Q34062498-00A1C53E-8E0B-4DA4-BA10-6B46F71F9F36

Q34062498-1A78D18E-9F44-4E5F-912C-1057F45D616D

Q34062498-29F208AE-C5E6-4517-AA0A-F656CE55674A

Q34062498-3B01E22F-4013-4B25-99EF-383619621DF8

Q34062498-47522627-FA2A-491D-A44D-028C2422A3F2

Q34062498-63BCCF8A-F68C-4FC3-9BB2-9106A7E34246

Q34062498-6F46192D-54C8-4E0C-9073-99315A471AA6

Q34062498-8FDC0A7B-79C2-485D-A2D6-AAAA975DAFAE

Q34062498-9238556E-3DED-40A6-8774-88D18F3574E1

Q34062498-A35876C9-2FF5-4835-98F6-BD00C4DA53D2

P2860

Q34062498-1025D9CC-F5AD-41C4-9223-34C1A1553031

Q34062498-24A7B631-B470-45E6-86C4-CDC9C0E6E37B

Q34062498-2972C980-551F-47A5-B373-BFB1D444458C

Q34062498-2A37D47B-776D-4CA6-935E-E1F05BE3974B

Q34062498-2C6CDCF3-4349-4D73-828B-E59014EB1E4C

Q34062498-2D8B779E-72D9-4185-9EBA-2641B13DBAA7

Q34062498-3215375A-8E45-4A06-8F91-91810C69325F

Q34062498-38202A40-8954-469C-9796-0067523F9446

Q34062498-3E1E301E-7ED2-447E-80B3-CFDDD896B010

Q34062498-41463138-7D19-4374-8413-9A4DE6B32BD8

P304

Q34062498-24F54DB0-F358-43EF-8D39-F71E2F37C94F

P31

Q34062498-9B70C203-18B2-4B1C-BCF5-7E598D0C094E

P356

Q34062498-2F935D40-F6C1-48C3-832D-F307B21537CD

P407

Q34062498-83BA7347-9E07-4852-9F71-2EFB7B18C28E

P433

Q34062498-5C7DED35-5049-4802-977E-6042C7169BFE

P478

Q34062498-252035F6-913E-4C2F-BABC-3E923FBB91A8

P50

Q34062498-CE8B45B0-24BE-4DEC-8AC9-395909722451

P577

Q34062498-3252A50E-7B5D-44FB-BD51-1BBD30734B14

P698

Q34062498-38A800FC-5FAE-4122-A21E-685606A4DBFC

P932

Q34062498-44B391B5-7E73-403B-B441-8F66A4DDF8A7

P356

1078-0432.CCR-09-3352

P1433

Clinical Cancer Research

P1476

Nrf2 and Keap1 abnormalities i ...... th clinicopathologic features.

@en

P2093

Alejandro H Corvalan

http://www.w3.org/2001/XMLSchema#string

B Nebiyou Bekele

http://www.w3.org/2001/XMLSchema#string

Carmen Behrens

http://www.w3.org/2001/XMLSchema#string

Cesar A Moran

http://www.w3.org/2001/XMLSchema#string

David J Stewart

http://www.w3.org/2001/XMLSchema#string

John D Minna

http://www.w3.org/2001/XMLSchema#string

Luisa M Solis

http://www.w3.org/2001/XMLSchema#string

Milind Suraokar

http://www.w3.org/2001/XMLSchema#string

Natalie C Ozburn

http://www.w3.org/2001/XMLSchema#string

Shyam Biswal

http://www.w3.org/2001/XMLSchema#string

P2860

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

Cancer statistics, 2008

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

Expression of the fetal Alz-50 clone 1 protein induces apoptotic cell death

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

P304

3743-3753

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/1078-0432.CCR-09-3352

http://www.w3.org/2001/XMLSchema#string

P407

P433

14

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P50

Ignacio I Wistuba

P577

2010-06-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20534738

http://www.w3.org/2001/XMLSchema#string

P932

2920733

http://www.w3.org/2001/XMLSchema#string