Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene
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PR72, a novel regulator of Wnt signaling required for Naked cuticle functionThe tumor suppressor PP2A Abeta regulates the RalA GTPaseIdentification of PP2A complexes and pathways involved in cell transformationPP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolutionTargeting protein serine/threonine phosphatases for drug developmentThe broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillanceProtein Phosphatase 2A as a Therapeutic Target in Acute Myeloid LeukemiaStructural Basis of PP2A Inhibition by Small t AntigenPP2A: The Wolf in Sheep's Clothing?Transcriptional regulation of PP2A-A alpha is mediated by multiple factors including AP-2alpha, CREB, ETS-1, and SP-1Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling.Physiological regulation of Akt activity and stability.A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2APhosphorylated protein phosphatase 2A determines poor outcome in patients with metastatic colorectal cancer.Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A.PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development.Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Functional genetic polymorphisms in PP2A subunit genes confer increased risks of lung cancer in southern and eastern Chinese.Therapeutic Re-Activation of Protein Phosphatase 2A in Acute Myeloid LeukemiaHuman cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice.Phosphatases: the new brakes for cancer development?Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.Mouse model for probing tumor suppressor activity of protein phosphatase 2A in diverse signaling pathways.Signalling by protein phosphatases and drug development: a systems-centred view.Overexpression of PP2A inhibitor SET oncoprotein is associated with tumor progression and poor prognosis in human non-small cell lung cancer.MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancerThe emerging role of the PI3-K-Akt pathway in prostate cancer progression.PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in CancerImpaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway.Protein phosphatase 2A isoforms utilizing Aβ scaffolds regulate differentiation through control of Akt protein.Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.The role of PP2A A subunits in tumor suppressionAssembly and structure of protein phosphatase 2A.Protein phosphatase 2A: a target for anticancer therapy.PP2A-Mediated Anticancer Therapy.All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function.Ligands for Ser/Thr phosphoprotein phosphatases: a patent review (2005-2015).
P2860
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P2860
Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Alterations in protein phospha ...... ons in the A beta subunit gene
@ast
Alterations in protein phospha ...... ons in the A beta subunit gene
@en
Alterations in protein phospha ...... ons in the A beta subunit gene
@nl
type
label
Alterations in protein phospha ...... ons in the A beta subunit gene
@ast
Alterations in protein phospha ...... ons in the A beta subunit gene
@en
Alterations in protein phospha ...... ons in the A beta subunit gene
@nl
prefLabel
Alterations in protein phospha ...... ons in the A beta subunit gene
@ast
Alterations in protein phospha ...... ons in the A beta subunit gene
@en
Alterations in protein phospha ...... ons in the A beta subunit gene
@nl
P2093
P2860
P3181
P356
P1433
P1476
Alterations in protein phospha ...... ons in the A beta subunit gene
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1204279
P407
P577
2001-04-05T00:00:00Z
P5875
P6179
1036237077