Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa.
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Werner syndrome protein interacts functionally with translesion DNA polymerasesEukaryotic translesion polymerases and their roles and regulation in DNA damage toleranceMinor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1, N 2 -γ-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage,NMR Structure and Dynamics of the C-Terminal Domain from Human Rev1 and Its Complex with Rev1 Interacting Region of DNA Polymerase ηDNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cellsThe N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesionsPreferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion.Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammalsHuman cancers express mutator phenotypes: origin, consequences and targeting.Master molecule, heal thyself.Convergence of Rad6/Rad18 and Fanconi anemia tumor suppressor pathways upon DNA damagePCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.Structural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity.Analysis of strand transfer and template switching mechanisms of DNA gap repair by homologous recombination in Escherichia coli: predominance of strand transfer.The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin.The roles of DNA polymerases κ and ι in the error-free bypass of N2-carboxyalkyl-2'-deoxyguanosine lesions in mammalian cells.DNA lesion identity drives choice of damage tolerance pathway in murine cell chromosomes.DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity.Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability.Noncognate DNA damage prevents the formation of the active conformation of the Y-family DNA polymerases DinB and DNA polymerase κWhat a difference a decade makes: insights into translesion DNA synthesis.Suffering in silence: the tolerance of DNA damage.Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.Genomic assay reveals tolerance of DNA damage by both translesion DNA synthesis and homology-dependent repair in mammalian cells.Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts.DNA sequence context greatly affects the accuracy of bypass across an ultraviolet light 6-4 photoproduct in mammalian cellsEffects of the N terminus of mouse DNA polymerase κ on the bypass of a guanine-benzo[a]pyrenyl adductInteraction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis.DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.Lesion processing: high-fidelity versus lesion-bypass DNA polymerasesSeparate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cellsDNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.Role of structural and energetic factors in regulating repair of a bulky DNA lesion with different opposite partner bases.Repair of gaps opposite lesions by homologous recombination in mammalian cells.Polk mutant mice have a spontaneous mutator phenotype.Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.DNA polymerase kappa protects human cells against MMC-induced genotoxicity through error-free translesion DNA synthesis
P2860
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P2860
Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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name
Quantitative analysis of trans ...... role of DNA polymerase kappa.
@en
type
label
Quantitative analysis of trans ...... role of DNA polymerase kappa.
@en
prefLabel
Quantitative analysis of trans ...... role of DNA polymerase kappa.
@en
P2093
P2860
P356
P1476
Quantitative analysis of trans ...... role of DNA polymerase kappa.
@en
P2093
Errol C Friedberg
Moshe Goldsmith
Nicholas Geacintov
Sharon Avkin
Susana Velasco-Miguel
Zvi Livneh
P2860
P304
53298-53305
P356
10.1074/JBC.M409155200
P407
P577
2004-10-09T00:00:00Z