Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function
about
Activation of interferon regulatory factor 5 by site specific phosphorylationCharacterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequencesThe IRF family, revisitedRotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7Plasmacytoid dendritic cells and type I IFN: 50 years of convergent historyInsights into interferon regulatory factor activation from the crystal structure of dimeric IRF5Endogenous retroviral promoter exaptation in human cancerA common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosusIRF5 promotes inflammatory macrophage polarization and TH1-TH17 responsesCritical role of IRF-5 in regulation of B-cell differentiation.Structural insights into interferon regulatory factor activation.IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosusPlasmacytoid dendritic cells in HIV infection: striking a delicate balance.Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infectionInterferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.Gender-dependent expression of murine Irf5 gene: implications for sex bias in autoimmunityRNA-Seq for enrichment and analysis of IRF5 transcript expression in SLE.Interferon regulatory factor 4 (IRF-4) targets IRF-5 to regulate Epstein-Barr virus transformation.Interferon regulatory factors: critical mediators of human lupus.Genetic polymorphism of interferon regulatory factor 5 (IRF5) correlates with allograft acute rejection of liver transplantation.Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus.Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression.Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.Onco-exaptation of an endogenous retroviral LTR drives IRF5 expression in Hodgkin lymphoma.Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferonsReplication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population.Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis.Mangiferin inhibits macrophage classical activation via downregulating interferon regulatory factor 5 expression.Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent.Activation of plasmacytoid dendritic cells.Genetics of myasthenia gravis: a case-control association study in the Hellenic population.Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease.Interferon regulatory factor-5-regulated pathways as a target for colorectal cancer therapeutics.Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupusRETRACTED: The COP9 signalosome interacts with and regulates interferon regulatory factor 5 protein stability.Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response.The interferon regulatory factor family in host defense: mechanism of action.The role of type I interferon production by dendritic cells in host defense.Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
P2860
Q24307504-446A642C-FA21-4111-853C-D2941CAE1524Q24656272-28814EF7-725E-4317-87E2-2658A9A04D43Q24678497-988903F8-6182-4598-A6CB-511E0AF65AABQ24683021-D8B3CE7C-33AF-4A36-8330-273EFAAFCCE5Q27485637-D2871841-1555-48FD-9589-8BAC46247333Q27652424-5D555E6B-81FB-494D-A69F-347C419A9915Q28067477-968400F4-C95C-4AA0-960B-AC219DA81E3FQ28236839-2B7D54CC-42A6-49CB-9742-A9DD35D0BBD7Q28303437-86D81B37-405A-4250-8593-2CF3D31C55C5Q33740745-A63FE35E-4CFB-495A-9B22-C78BADEEDB8BQ33756083-30E899D3-56C3-476E-9A50-8AB62BEB4C1BQ33804141-E0B30999-1DFE-4D3A-AAED-F324C333E7F5Q33805319-26F5A367-26DC-448F-8242-BD72574F0766Q33900037-D05060E8-01F5-4460-971D-D320D2B5ED9BQ33975488-3227AA5B-97E9-4691-9D26-C32010D23DDEQ34187236-C5D31D3C-7140-44FF-A576-C6005D240F60Q34563170-187ACE1D-2B1A-4CA3-8DB4-7B634988A8B1Q34979127-6FF66448-CB5C-43D5-A6D7-E9C4717978CBQ35014051-8BF9A16F-349B-4B0A-950B-F2282D988B6FQ35161570-3F0E5C02-BD71-4E8B-A0C8-C569226E1A69Q35542816-8C6B0701-4E0D-4751-A632-8F17C0CFA8B9Q35599579-5E416C2B-7001-4CE4-95A4-C404A2AEF4DAQ35741943-D384C0F0-35C0-493B-8833-4DB9626D90D5Q35747495-28B94741-EFB3-48D4-A676-E6E3B6E7A8DDQ35784689-FC7A5B78-F460-4D7B-8EDF-131E3E002201Q35869000-5D273834-90DA-4A69-AFAC-43754C87D66FQ35889581-FDDD6376-1BC2-4729-B83F-23D718138CCDQ36045366-6EE69BEB-2858-404D-8515-AE9DC5601EFCQ36234001-7F45B8C5-59B1-4C7F-8424-3668C7E2C964Q36262301-08D602DE-3E5F-4885-87F5-456DD33CD94EQ36294292-817A18DF-2AAA-47C7-B895-51345D959AADQ36302403-E916D37B-3EFA-44AC-B3E7-462BD6429529Q36421994-BF156E87-689C-47DE-AB56-D7EC5A390574Q36499242-B946465E-0A50-4864-A7D1-DE79C99F615CQ36632390-E1128B97-E600-4300-BA4F-5585A17737E2Q36667465-595FE1A6-4331-4819-94A0-F0BD28A262A8Q36773380-5580A219-AA77-4648-8FCD-14224F6BEE77Q36821757-785B76EF-A1DD-4C3B-8F8D-DAE49B86D36DQ36838232-B7A52ADE-805A-47B1-9CCA-025F5B781C88Q36930892-51C0EE5F-B298-43C9-844D-B8271F965910
P2860
Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function
description
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2005
@ast
im Juni 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 3 June 2005)
@en
vedecký článok (publikovaný 2005/06/03)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/06/03)
@nl
наукова стаття, опублікована в червні 2005
@uk
name
Two discrete promoters regulat ...... tion, regulation, and function
@ast
Two discrete promoters regulat ...... tion, regulation, and function
@en
Two discrete promoters regulat ...... tion, regulation, and function
@nl
type
label
Two discrete promoters regulat ...... tion, regulation, and function
@ast
Two discrete promoters regulat ...... tion, regulation, and function
@en
Two discrete promoters regulat ...... tion, regulation, and function
@nl
prefLabel
Two discrete promoters regulat ...... tion, regulation, and function
@ast
Two discrete promoters regulat ...... tion, regulation, and function
@en
Two discrete promoters regulat ...... tion, regulation, and function
@nl
P2093
P3181
P356
P1476
Two discrete promoters regulat ...... tion, regulation, and function
@en
P2093
Betsy J Barnes
Guodong Hu
Katherine Hoops
Margo E Mancl
Niquiche Sangster-Guity
Patricia Fitzgerald-Bocarsly
Paula M Pitha
Stacey L Olshalsky
P304
21078-21090
P3181
P356
10.1074/JBC.M500543200
P407
P577
2005-03-31T00:00:00Z