Membrane topology of the human Na+/glucose cotransporter SGLT1
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Defects in Na+/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorptionCongenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice siteStructure-function analysis of the bestrophin family of anion channelsVisualizing functional motions of membrane transporters with molecular dynamics simulationsThe functional unit of the renal type IIa Na+/Pi cotransporter is a monomerInteraction of the type IIa Na/Pi cotransporter with PDZ proteinsThe membrane topology of GAT-1, a (Na+ + Cl-)-coupled gamma-aminobutyric acid transporter from rat brainEssential cysteine residues of the type IIa Na+/Pi cotransporterProtein kinase C activators induce membrane retrieval of type II Na+-phosphate cotransporters expressed in Xenopus oocytesIdentification of functionally important sites in the first intracellular loop of the NaPi-IIa cotransporterMembrane topology and insertion of membrane proteins: search for topogenic signalsA gate-free pathway for substrate release from the inward-facing state of the Na⁺-galactose transporterNeutralization of a conserved amino acid residue in the human Na+/glucose transporter (hSGLT1) generates a glucose-gated H+ channel.Three surface subdomains form the vestibule of the Na+/glucose cotransporter SGLT1.Employing Escherichia coli to functionally express, purify, and characterize a human transporterSGLT1, a novel cardiac glucose transporter, mediates increased glucose uptake in PRKAG2 cardiomyopathySodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.Structural biology and function of solute transporters: implications for identifying and designing substrates.The Human Sodium-Glucose Cotransporter (hSGLT1) Is a Disulfide-Bridged Homodimer with a Re-Entrant C-Terminal LoopIdentification of a disulfide bridge linking the fourth and the seventh extracellular loops of the Na+/glucose cotransporterStructural analysis of cloned plasma membrane proteins by freeze-fracture electron microscopy.Transport function of the renal type IIa Na+/P(i) cotransporter is codetermined by residues in two opposing linker regions.Properties of the mutant Ser-460-Cys implicate this site in a functionally important region of the type IIa Na(+)/P(i) cotransporter proteinCysteine mutagenesis reveals novel structure-function features within the predicted third extracellular loop of the type IIa Na(+)/P(i) cotransporterStructure-function relations of the first and fourth predicted extracellular linkers of the type IIa Na+/Pi cotransporter: I. Cysteine scanning mutagenesis.Conformational changes couple Na+ and glucose transportTransmembrane topology of a CLC chloride channel.Transmembrane IV of the high-affinity sodium-glucose cotransporter participates in sugar bindingGene structure and functional analysis of the human Na+/phosphate co-transporter.Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresisTwo PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function.SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states.Diurnal expression of the rat intestinal sodium-glucose cotransporter 1 (SGLT1) is independent of local luminal factors.The effects of food components on hormonal signalling in gastrointestinal enteroendocrine cells.Transmembrane folding of the human erythrocyte anion exchanger (AE1, Band 3) determined by scanning and insertional N-glycosylation mutagenesis.The sodium/multivitamin transporter: a multipotent system with therapeutic implications.Glycosylation of solute carriers: mechanisms and functional consequences.GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters.Single molecule recognition of protein binding epitopes in brush border membranes by force microscopy.Membrane integration and topology of the first transmembrane segment in normal and Southeast Asian ovalocytosis human erythrocyte anion exchanger 1.
P2860
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P2860
Membrane topology of the human Na+/glucose cotransporter SGLT1
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Membrane topology of the human Na+/glucose cotransporter SGLT1
@ast
Membrane topology of the human Na+/glucose cotransporter SGLT1
@en
Membrane topology of the human Na+/glucose cotransporter SGLT1
@nl
type
label
Membrane topology of the human Na+/glucose cotransporter SGLT1
@ast
Membrane topology of the human Na+/glucose cotransporter SGLT1
@en
Membrane topology of the human Na+/glucose cotransporter SGLT1
@nl
prefLabel
Membrane topology of the human Na+/glucose cotransporter SGLT1
@ast
Membrane topology of the human Na+/glucose cotransporter SGLT1
@en
Membrane topology of the human Na+/glucose cotransporter SGLT1
@nl
P2093
P3181
P356
P1476
Membrane topology of the human Na+/glucose cotransporter SGLT1
@en
P2093
P304
P3181
P356
10.1074/JBC.271.4.1925
P407
P577
1996-01-01T00:00:00Z