Neutralization of a conserved amino acid residue in the human Na+/glucose transporter (hSGLT1) generates a glucose-gated H+ channel.
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A glucose sensor hiding in a family of transportersVisualizing functional motions of membrane transporters with molecular dynamics simulationsModeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologueThe mechanism of sodium and substrate release from the binding pocket of vSGLTMutation K448E in the external loop 5 of rat GABA transporter rGAT1 induces pH sensitivity and alters substrate interactionsH+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestineEmploying Escherichia coli to functionally express, purify, and characterize a human transporterAn antiport mechanism for a member of the cation diffusion facilitator family: divalent cations efflux in exchange for K+ and H+.The sodium/substrate symporter family: structural and functional features.Conserved tyrosine in the first transmembrane segment of solute:sodium symporters is involved in Na+-coupled substrate co-transport.Metadynamics simulations reveal a Na+ independent exiting path of galactose for the inward-facing conformation of vSGLTMonitoring the function of membrane transport proteins in detergent-solubilized form.Interaction of α-Lipoic Acid with the Human Na+/Multivitamin Transporter (hSMVT).Bridging the gap between structure and kinetics of human SGLT1.Conformational dynamics of hSGLT1 during Na+/glucose cotransportPerturbation analysis of the voltage-sensitive conformational changes of the Na+/glucose cotransporter.Regulation of AE2-mediated Cl- transport by intracellular or by extracellular pH requires highly conserved amino acid residues of the AE2 NH2-terminal cytoplasmic domainThe importance of being aromatic: π interactions in sodium symportersNa+ coordination at the Na2 site of the Na+/I- symporter.Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3Functional identification and characterization of sodium binding sites in Na symporters.Structure and function of Na(+)-symporters with inverted repeats.The sodium/multivitamin transporter: a multipotent system with therapeutic implications.A monocarboxylate permease of Rhizobium leguminosarum is the first member of a new subfamily of transporters.Surprising substrate versatility in SLC5A6: Na+-coupled I- transport by the human Na+/multivitamin transporter (hSMVT).Ion-releasing state of a secondary membrane transporter.State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.Amino acid transporter CAATCH1 is also an amino acid-gated cation channel.Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods.Mobility of ions, sugar, and water in the cytoplasm of Xenopus oocytes expressing Na(+)-coupled sugar transporters (SGLT1).Zinc potentiates an uncoupled anion conductance associated with the dopamine transporter.Determination of transport stoichiometry for two cation-coupled myo-inositol cotransporters: SMIT2 and HMIT.Effect of pH on L- and D-methionine uptake across the apical membrane of Caco-2 cells.Carrier and channel properties of the mitochondrial transporters: physiology and pathology?An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling.Conserved glutamate residues are critically involved in Na+/nucleoside cotransport by human concentrative nucleoside transporter 1 (hCNT1).Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
P2860
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P2860
Neutralization of a conserved amino acid residue in the human Na+/glucose transporter (hSGLT1) generates a glucose-gated H+ channel.
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Neutralization of a conserved ...... es a glucose-gated H+ channel.
@ast
Neutralization of a conserved ...... es a glucose-gated H+ channel.
@en
type
label
Neutralization of a conserved ...... es a glucose-gated H+ channel.
@ast
Neutralization of a conserved ...... es a glucose-gated H+ channel.
@en
prefLabel
Neutralization of a conserved ...... es a glucose-gated H+ channel.
@ast
Neutralization of a conserved ...... es a glucose-gated H+ channel.
@en
P2093
P2860
P356
P1476
Neutralization of a conserved ...... es a glucose-gated H+ channel.
@en
P2093
P2860
P304
P356
10.1074/JBC.M005521200
P407
P577
2000-10-06T00:00:00Z