Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia
about
MxA overexpression reveals a common genetic link in four Fanconi anemia complementation groupsDisruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin CHow the fanconi anemia pathway guards the genomeDisease-specific induced pluripotent stem cellsFanconi anaemiaFanconi anemia genes are highly expressed in primitive CD34+ hematopoietic cellsModeling the study of DNA damage responses in miceLearning from a paradox: recent insights into Fanconi anaemia through studying mouse modelsThe Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 PhosphorylationEpithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout miceThe Fanconi anaemia/BRCA pathwayA novel ubiquitin ligase is deficient in Fanconi anemiaCharacterization, expression and complex formation of the murine Fanconi anaemia gene product FancgMouse models of Fanconi anemiaConcomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalusThe Fanconi anemia pathway and ubiquitinUse of DNA repair-deficient XPA transgenic mice in short-term carcinogenicity testing.Functional activity of the fanconi anemia protein FAA requires FAC binding and nuclear localization.Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.FANCC suppresses short telomere-initiated telomere sister chromatid exchangeNucleophosmin suppresses oncogene-induced apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability.Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis.Congenital bone marrow failure syndromes.Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repairHuman FANCC is hypomorphic in murine Fancc-deficient cellsErythropoiesis: Current Clinical Practice: Advances in the Genetics and Biology of Fanconi Anaemia.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes.Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonistFANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.The phenotype of FancB-mutant mouse embryonic stem cells.Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress.Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.Overcoming reprogramming resistance of Fanconi anemia cells.TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.Survival of the fittest: in vivo selection and stem cell gene therapyFANCA safeguards interphase and mitosis during hematopoiesis in vivo.The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.SCO2 Mediates Oxidative Stress-Induced Glycolysis to Oxidative Phosphorylation Switch in Hematopoietic Stem Cells
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P2860
Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia
description
1996 nî lūn-bûn
@nan
1996 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@ast
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@en
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@nl
type
label
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@ast
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@en
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@nl
prefLabel
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@ast
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@en
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@nl
P2093
P2860
P3181
P356
P1433
P1476
Inactivation of Fac in mice pr ...... reminiscent of Fanconi anaemia
@en
P2093
A Auerbach
A L Joyner
C J Guidos
D J Tomkins
H Youssoufian
M Buchwald
P2860
P2888
P304
P3181
P356
10.1038/NG0496-448
P407
P577
1996-04-01T00:00:00Z
P5875
P6179
1052174915