The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis
about
The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cellsGeminin regulates neuronal differentiation by antagonizing Brg1 activityRegulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidizationThe chromosome cycle: coordinating replication and segregation. Second in the cycles review series.Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damageReplication licensing and cancer--a fatal entanglement?Preventing re-replication of chromosomal DNA.The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cyclesLoss of Geminin induces rereplication in the presence of functional p53Functional domains of the Xenopus replication licensing factor Cdt1EndoreplicationCoinFLP: a system for efficient mosaic screening and for visualizing clonal boundaries in Drosophila.Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensingCellular checkpoint mechanisms monitoring proper initiation of DNA replicationThe anaphase promoting complex/cyclosome: a machine designed to destroyReplication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.Preferential re-replication of Drosophila heterochromatin in the absence of geminin.Geminin-deficient neural stem cells exhibit normal cell division and normal neurogenesis.Geminin deficiency causes a Chk1-dependent G2 arrest in Xenopus.Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition.Control of DNA replication and chromosome ploidy by geminin and cyclin AGeminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice.The Ecdysone receptor constrains wingless expression to pattern cell cycle across the Drosophila wing margin in a Cyclin B-dependent manner.Knockdown of SCF(Skp2) function causes double-parked accumulation in the nucleus and DNA re-replication in Drosophila plasmatocytes.Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions.A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus.Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cellsSafeguarding genetic information in Drosophila.The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complexAnalysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complexThe dynamics of replication licensing in live Caenorhabditis elegans embryos.From egg to gastrula: how the cell cycle is remodeled during the Drosophila mid-blastula transition.Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways.Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity.Control of Drosophila endocycles by E2F and CRL4(CDT2).Geminin is required for epithelial to mesenchymal transition at gastrulation.Visualization of replication initiation and elongation in DrosophilaDynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos.DNA replication licensing and cell cycle kinetics of normal and neoplastic breast.
P2860
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P2860
The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis
description
2001 nî lūn-bûn
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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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name
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@ast
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@en
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@nl
type
label
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@ast
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@en
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@nl
prefLabel
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@ast
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@en
The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@nl
P2093
P2860
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The Drosophila Geminin homolog ...... n anaphase and in neurogenesis
@en
P2093
P2860
P304
P356
10.1101/GAD.916201
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P577
2001-10-01T00:00:00Z