Control of DNA replication and chromosome ploidy by geminin and cyclin A - Wikidata - awgldk - TriplyDB

Control of DNA replication and chromosome ploidy by geminin and cyclin A

Control of DNA replication and chromosome ploidy by geminin and cyclin A

http://www.wikidata.org/entity/Q34323837

about

The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding Disruption of mechanisms that prevent rereplication triggers a DNA damage response Geminin regulates neuronal differentiation by antagonizing Brg1 activity Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidization The chromosome cycle: coordinating replication and segregation. Second in the cycles review series.Regulation of replication licensing by acetyltransferase Hbo1.Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint Prevention of DNA re-replication in eukaryotic cells Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity Replication licensing and cancer--a fatal entanglement?Selective killing of cancer cells by suppression of geminin activity Preventing re-replication of chromosomal DNA.Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1 Loss of Geminin induces rereplication in the presence of functional p53 Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma Functional domains of the Xenopus replication licensing factor Cdt1 The Non-Canonical Role of Aurora-A in DNA Replication Genomic instability in cancer.Re-replication of a centromere induces chromosomal instability and aneuploidy Replication fork instability and the consequences of fork collisions from rereplication Cellular checkpoint mechanisms monitoring proper initiation of DNA replication Novel roles for p53 in the genesis and targeting of tetraploid cancer cells Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis.Stress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factor An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.The APC/C inhibitor, Emi1, is essential for prevention of rereplication APC/C--the master controller of origin licensing?ATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication.Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses.Soaking RNAi in Bombyx mori BmN4-SID1 cells arrests cell cycle progression Preferential re-replication of Drosophila heterochromatin in the absence of geminin.Cell and plastid division are coordinated through the prereplication factor AtCDT1 CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication Specific replication origins promote DNA amplification in fission yeast.Geminin deficiency causes a Chk1-dependent G2 arrest in Xenopus.

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P2860

Control of DNA replication and chromosome ploidy by geminin and cyclin A

http://www.wikidata.org/entity/Q34323837

description

2002 nî lūn-bûn

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2002 թուականի Մարտին հրատարակուած գիտական յօդուած

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2002 թվականի մարտին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

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2002年論文

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2002年论文

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name

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@ast

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@en

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@nl

type

label

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@ast

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@en

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@nl

prefLabel

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@ast

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@en

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@nl

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P356

MCB.22.6.1868-1880.2002

P1433

Molecular and Cellular Biology

P1476

Control of DNA replication and chromosome ploidy by geminin and cyclin A

@en

P2093

Hui Zhang

http://www.w3.org/2001/XMLSchema#string

Ivailo S Mihaylov

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Jianyu Zheng

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Junko Tanaka

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Leigh Ann Higa

http://www.w3.org/2001/XMLSchema#string

Lynn Cooley

http://www.w3.org/2001/XMLSchema#string

Lynn Jones

http://www.w3.org/2001/XMLSchema#string

Naoto Minamino

http://www.w3.org/2001/XMLSchema#string

Sophia Ryzhikov

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Takeshi Kondo

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P2860

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

Geminin, an inhibitor of DNA replication, is degraded during mitosis

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis

Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

P304

1868-1880

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scholarly article

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10.1128/MCB.22.6.1868-1880.2002

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6

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22

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2002-03-01T00:00:00Z

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11865064

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135598

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