Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos.
about
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stabilityProtein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcriptionThe APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phaseGSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with AxinDifferential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobinInhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding proteinSynergistic activation of the Wnt signaling pathway by Dvl and casein kinase IepsilonActivation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signalingIdentification and characterization of a novel Dvl-binding protein that suppresses Wnt signalling pathwayAxin localizes to the centrosome and is involved in microtubule nucleationMutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancerDesumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin.Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathwayStructural basis of the Axin-adenomatous polyposis coli interactionCrystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complexThe links between axin and carcinogenesisDomains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localizationMolecular specification of germ layers in vertebrate embryosbeta-catenin signaling and cancerRGS7 and RGS8 differentially accelerate G protein-mediated modulation of K+ currentsDifferential interaction of plakoglobin and beta-catenin with the ubiquitin-proteasome systemAxin directly interacts with plakoglobin and regulates its stabilitybeta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formationCasein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-cateninAxin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathwayIdentification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domainProtein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in XenopusInteraction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction.A novel beta-catenin-binding protein inhibits beta-catenin-dependent Tcf activation and axis formationInhibition of Wnt signaling pathway by a novel axin-binding proteinNuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathwayWnt5a regulates distinct signalling pathways by binding to Frizzled2Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stabilityWnt-induced dephosphorylation of axin releases beta-catenin from the axin complexActivation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and GalphatInteraction among GSK-3, GBP, axin, and APC in Xenopus axis specificationWnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumorsGSK-3: Functional Insights from Cell Biology and Animal Models.Glycogen synthase kinase 3 and h-prune regulate cell migration by modulating focal adhesions.
P2860
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P2860
Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Axil, a member of the Axin fam ...... s formation of Xenopus embryos
@nl
Axil, a member of the Axin fam ...... formation of Xenopus embryos.
@ast
Axil, a member of the Axin fam ...... formation of Xenopus embryos.
@en
type
label
Axil, a member of the Axin fam ...... s formation of Xenopus embryos
@nl
Axil, a member of the Axin fam ...... formation of Xenopus embryos.
@ast
Axil, a member of the Axin fam ...... formation of Xenopus embryos.
@en
prefLabel
Axil, a member of the Axin fam ...... s formation of Xenopus embryos
@nl
Axil, a member of the Axin fam ...... formation of Xenopus embryos.
@ast
Axil, a member of the Axin fam ...... formation of Xenopus embryos.
@en
P2093
P2860
P3181
P356
P1476
Axil, a member of the Axin fam ...... formation of Xenopus embryos.
@en
P2093
H Yamamoto
M Asashima
P2860
P304
P3181
P356
10.1128/MCB.18.5.2867
P407
P577
1998-05-01T00:00:00Z