In vivo formation of a proton-sensitive K+ channel by heteromeric subunit assembly of Kir5.1 with Kir4.1
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Mislocalization of K+ channels causes the renal salt wasting in EAST/SeSAME syndromeSpecific localization of an inwardly rectifying K(+) channel, Kir4.1, at the apical membrane of rat gastric parietal cells; its possible involvement in K(+) recycling for the H(+)-K(+)-pumpDifferential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1EAST syndrome: Clinical, pathophysiological, and genetic aspects of mutations in KCNJ10Myelinating satellite oligodendrocytes are integrated in a glial syncytium constraining neuronal high-frequency activityIdentification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channelsGenetic and functional linkage of Kir5.1 and Kir2.1 channel subunitsIdentification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channelsInteraction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel functionAn inward rectifier K(+) channel at the basolateral membrane of the mouse distal convoluted tubule: similarities with Kir4-Kir5.1 heteromeric channelsKCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel functionInwardly rectifying potassium channel Kir4.1 is responsible for the native inward potassium conductance of satellite glial cells in sensory gangliaMAGI-1a functions as a scaffolding protein for the distal renal tubular basolateral K+ channelsKir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalisCloning, expression, and localization of a rat hepatocyte inwardly rectifying potassium channelMolecular diversity and regulation of renal potassium channels.Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Galphaq-coupled receptorsMolecular mechanisms of EAST/SeSAME syndrome mutations in Kir4.1 (KCNJ10)Genetic inactivation of Kcnj16 identifies Kir5.1 as an important determinant of neuronal PCO2/pH sensitivity.Molecular basis of decreased Kir4.1 function in SeSAME/EAST syndrome.Subunit-subunit interactions are critical for proton sensitivity of ROMK: evidence in support of an intermolecular gating mechanismMolecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome.The disruption of central CO2 chemosensitivity in a mouse model of Rett syndrome.Cellular mechanisms involved in CO(2) and acid signaling in chemosensitive neurons.Basolateral membrane K+ channels in renal epithelial cellsKir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells.Expression profiles of human epididymis epithelial cells reveal the functional diversity of caput, corpus and cauda regionsCloning and functional characterization of inward-rectifying potassium (Kir) channels from Malpighian tubules of the mosquito Aedes aegyptiNovel KCNJ10 Gene Variations Compromise Function of Inwardly Rectifying Potassium Channel 4.1.Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage.The expression, regulation, and function of Kir4.1 (Kcnj10) in the mammalian kidney.Src family protein tyrosine kinase regulates the basolateral K channel in the distal convoluted tubule (DCT) by phosphorylation of KCNJ10 protein.New perspective of ClC-Kb/2 Cl- channel physiology in the distal renal tubule.Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamineExpression of Kir4.1 and Kir5.1 inwardly rectifying potassium channels in oligodendrocytes, the myelinating cells of the CNS.The salt-wasting phenotype of EAST syndrome, a disease with multifaceted symptoms linked to the KCNJ10 K+ channel.Potassium channels in pancreatic duct epithelial cells: their role, function and pathophysiological relevance.Basolateral Kir4.1 activity in the distal convoluted tubule regulates K secretion by determining NaCl cotransporter activityVariable loss of Kir4.1 channel function in SeSAME syndrome mutations.
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P2860
In vivo formation of a proton-sensitive K+ channel by heteromeric subunit assembly of Kir5.1 with Kir4.1
description
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Juni 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/06/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/06/15)
@nl
наукова стаття, опублікована в червні 2000
@uk
مقالة علمية (نشرت في 15-6-2000)
@ar
name
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@ast
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@en
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@nl
type
label
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@ast
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@en
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@nl
prefLabel
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@ast
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@en
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@nl
P2093
P2860
P3181
P1476
In vivo formation of a proton- ...... assembly of Kir5.1 with Kir4.1
@en
P2093
A. Inanobe
M. Tanemoto
N. Kittaka
Y. Kurachi
P2860
P304
P3181
P356
10.1111/J.1469-7793.2000.00587.X
P407
P478
P577
2000-06-15T00:00:00Z