Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic - Wikidata - awgldk - TriplyDB

Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic

Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic

http://www.wikidata.org/entity/Q28583370

about

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells The crystal structure of the phosphatidylinositol 4-kinase IIα Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes Phosphoinositides: tiny lipids with giant impact on cell regulation PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes.Structural Basis of the Intracellular Sorting of the SNARE VAMP7 by the AP3 Adaptor Complex The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design Genome-wide analysis of AP-3-dependent protein transport in yeast Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms Cinderella story: PI4P goes from precursor to key signaling molecule Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampus Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles Differential Targeting of SLC30A10/ZnT10 Heterodimers to Endolysosomal Compartments Modulates EGF-Induced MEK/ERK1/2 Activity Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes.Loss of phosphatidylinositol 4-kinase 2alpha activity causes late onset degeneration of spinal cord axons Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity.A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking.Endosomal recycling regulates Anthrax Toxin Receptor 1/Tumor Endothelial Marker 8-dependent cell spreading.An AP-3-dependent mechanism drives synaptic-like microvesicle biogenesis in pancreatic islet beta-cells.Isolation of labile multi-protein complexes by in vivo controlled cellular cross-linking and immuno-magnetic affinity chromatography PI4KIIalpha is a novel regulator of tumor growth by its action on angiogenesis and HIF-1alpha regulation.Endosomal sorting of VAMP3 is regulated by PI4K2A.Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase.Oxysterol binding protein-dependent activation of sphingomyelin synthesis in the golgi apparatus requires phosphatidylinositol 4-kinase IIα.Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase II{alpha}Phosphoinositide signaling: new tools and insights.Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network.Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis.Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene.Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.Molecular brightness analysis reveals phosphatidylinositol 4-Kinase IIβ association with clathrin-coated vesicles in living cells.Notch signaling from the endosome requires a conserved dileucine motif.

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P2860

Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic

http://www.wikidata.org/entity/Q28583370

description

2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2008

@ast

im April 2008 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2008/04/01)

@sk

vědecký článek publikovaný v roce 2008

@cs

wetenschappelijk artikel (gepubliceerd op 2008/04/01)

@nl

наукова стаття, опублікована у квітні 2008

@uk

مقالة علمية (نشرت في أبريل 2008)

@ar

name

Phosphatidylinositol-4-kinase ...... required for endosome traffic

@ast

Phosphatidylinositol-4-kinase ...... required for endosome traffic

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Phosphatidylinositol-4-kinase ...... required for endosome traffic

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type

label

Phosphatidylinositol-4-kinase ...... required for endosome traffic

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Phosphatidylinositol-4-kinase ...... required for endosome traffic

@en

Phosphatidylinositol-4-kinase ...... required for endosome traffic

@nl

prefLabel

Phosphatidylinositol-4-kinase ...... required for endosome traffic

@ast

Phosphatidylinositol-4-kinase ...... required for endosome traffic

@en

Phosphatidylinositol-4-kinase ...... required for endosome traffic

@nl

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MBC.E07-12-1239

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Molecular Biology of the Cell

P1476

Phosphatidylinositol-4-kinase ...... required for endosome traffic

@en

P2093

Branch Craige

http://www.w3.org/2001/XMLSchema#string

Gloria Salazar

http://www.w3.org/2001/XMLSchema#string

P2860

VAMP-7 mediates vesicular transport from endosomes to lysosomes

Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor

Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages

AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes

Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.

Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes

A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3.

Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum

The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform

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1415–1426

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scholarly article

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2381818

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10.1091/MBC.E07-12-1239

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4

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19

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2008-04-01T00:00:00Z

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5596499

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18256276

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2291421

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