Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
about
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitinationStabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX proteinThe RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complexCells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycleThe human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding proteinStabilization and activation of p53 by the coactivator protein TAFII31The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradationTBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescenceNovel nucleolar pathway connecting intracellular energy status with p53 activationHDM2-binding partners: interaction with translation elongation factor EF1alpha.Antiviral action of the tumor suppressor ARFCARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability14-3-3 Binding to Pim-phosphorylated Ser166 and Ser186 of human Mdm2--Potential interplay with the PKB/Akt pathway and p14(ARF)A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2Mutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stabilityAlternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback controlTyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulationDesumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin.MDM2-HDAC1-mediated deacetylation of p53 is required for its degradationCOP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin systemSupramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced responseRibosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionRegulation of the 26S proteasome by adenovirus E1ATwist is a potential oncogene that inhibits apoptosisp53-independent functions of the p19(ARF) tumor suppressorBmi1, stem cells, and senescence regulationA TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback controlAberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2p53 acetylation is crucial for its transcription-independent proapoptotic functionsRegulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanismMutant p53 proteins bind DNA in a DNA structure-selective modep14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomesp19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathwaysp14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2Towards a Better Understanding of the Molecular Mechanisms Involved in Sunlight-Induced MelanomaResponses of genes involved in cell cycle control to diverse DNA damaging chemicals in human lung adenocarcinoma A549 cells.Clinical Overview of MDM2/X-Targeted TherapiesMicroRNA Regulation of Human Breast Cancer Stem CellsDeubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1
P2860
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P2860
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53
@nl
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53.
@ast
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53.
@en
type
label
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53
@nl
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53.
@ast
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53.
@en
prefLabel
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53
@nl
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53.
@ast
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53.
@en
P2860
P356
P1433
P1476
Association of p19(ARF) with M ...... Mdm2 for tumor suppressor p53.
@en
P2093
P2860
P356
10.1093/EMBOJ/18.1.22
P407
P577
1999-01-01T00:00:00Z