The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice
about
Linking human diseases to animal models using ontology-based phenotype annotationThe structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signalingCdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiationA small molecule that binds Hedgehog and blocks its signaling in human cellsEstablishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedbackHedgehog Signaling in Pancreatic Fibrosis and CancerHedgehog signaling and maintenance of homeostasis in the intestinal epitheliumSonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activityCdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in miceIn vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probeThe mode of Hedgehog binding to Ihog homologues is not conserved across different phylaHedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active SiteRegulation by miR181 family of the dependence receptor CDON tumor suppressive activity in neuroblastomaSonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothenedA sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminencesStructural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancerGas1 extends the range of Hedgehog action by facilitating its signalingGas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehogThe Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse developmentOcular abnormalities in mice lacking the immunoglobulin superfamily member CdoN-cadherin ligation, but not Sonic hedgehog binding, initiates Cdo-dependent p38alpha/beta MAPK signaling in skeletal myoblastsMechanisms that underlie co-variation of the brain and faceDistinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathwaysPersistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.Cdon promotes neural crest migration by regulating N-cadherin localization.Single median maxillary central incisor: new data and mutation review.Differential screening identifies transcripts with depot-dependent expression in white adipose tissues.Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic HedgehogUsing mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway.Genetic and biochemical definition of the Hedgehog receptor.The molecular genetics of holoprosencephaly.Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.Hedgehog signaling in the normal and neoplastic mammary gland.Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.Mechanism and evolution of cytosolic Hedgehog signal transductionCdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicleBoc modifies the spectrum of holoprosencephaly in the absence of Gas1 functionKinetic and structural studies on interactions between heparin or heparan sulfate and proteins of the hedgehog signaling pathway.Dynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life.
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P2860
The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice
description
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Mai 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2006/05/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/05/01)
@nl
наукова стаття, опублікована в травні 2006
@uk
مقالة علمية (نشرت في مايو 2006)
@ar
name
The cell surface membrane prot ...... y and feedback network in mice
@ast
The cell surface membrane prot ...... y and feedback network in mice
@en
The cell surface membrane prot ...... y and feedback network in mice
@nl
type
label
The cell surface membrane prot ...... y and feedback network in mice
@ast
The cell surface membrane prot ...... y and feedback network in mice
@en
The cell surface membrane prot ...... y and feedback network in mice
@nl
prefLabel
The cell surface membrane prot ...... y and feedback network in mice
@ast
The cell surface membrane prot ...... y and feedback network in mice
@en
The cell surface membrane prot ...... y and feedback network in mice
@nl
P2093
P1433
P1476
The cell surface membrane prot ...... y and feedback network in mice
@en
P2093
Andrew P McMahon
Benjamin L Allen
Jong-Sun Kang
Robert S Krauss
Toyoaki Tenzen
P304
P356
10.1016/J.DEVCEL.2006.04.004
P407
P577
2006-04-27T00:00:00Z