UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.
about
Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissuesPAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cellsKinectin is a key effector of RhoG microtubule-dependent cellular activityOligomerization of DH domain is essential for Dbl-induced transformationSmall GTPase RhoG is a key regulator for neurite outgrowth in PC12 cellsThe DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activationDissecting Nck/Dock signaling pathways in Drosophila visual system.Function and regulation of the Rho guanine nucleotide exchange factor TrioA network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegansRHGF-2 is an essential Rho-1 specific RhoGEF that binds to the multi-PDZ domain scaffold protein MPZ-1 in Caenorhabditis elegansThe Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidancepix-1 controls early elongation in parallel with mel-11 and let-502 in Caenorhabditis elegansStructure and mutagenesis of the Dbl homology domainCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Expression of receptor tyrosine phosphatases during development of the retinotectal projection of the chickThe trio guanine nucleotide exchange factor is a RhoA target. Binding of RhoA to the trio immunoglobulin-like domainAssociation of the proto-oncogene product dbl with G protein betagamma subunitsReceptor protein tyrosine phosphatases in nervous system developmentPAK4 kinase is essential for embryonic viability and for proper neuronal developmentThe C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipidsInhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexesStructure and expression of murine mgcRacGAP: its developmental regulation suggests a role for the Rac/MgcRacGAP signalling pathway in neurogenesisIsoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation siteIdentification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growthIdentification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42Control of dendritic morphogenesis by Trio in Drosophila melanogasterRegulation of Kalirin by Cdk5Signaling between focal adhesion kinase and trio.Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum.Profiling a Caenorhabditis elegans behavioral parametric dataset with a supervised K-means clustering algorithm identifies genetic networks regulating locomotion.The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP.Gene expression of Caenorhabditis elegans neurons carries information on their synaptic connectivity.Discovery of transcription factors and other candidate regulators of neural crest developmentDevelopmental genetics of the C. elegans pharyngeal neurons NSML and NSMR.Kalirin12 interacts with dynamin.C. elegans ten-1 is synthetic lethal with mutations in cytoskeleton regulators, and enhances many axon guidance defective mutants.Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain developmentThe Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis
P2860
Q24291372-BBFAFC7E-5D12-4E18-870D-DDD7A83AB4DAQ24540039-BF59EF1D-7736-4339-BAE2-FDCCDC68404DQ24548259-BA72A6B2-1500-4C0D-892F-FC4A51EE54FBQ24551032-C148D919-3550-4E72-8530-EA8DC22E2804Q24551209-AA650BE6-CBB1-4570-8C21-646A7F4C9690Q24675414-B657C557-AA97-4847-8146-5FD585480D84Q24810133-073272B9-B9B9-48F4-B078-1C5F2D332808Q26995528-23574475-9FBA-40C7-85B7-3502FC73EF0EQ27306247-54AEA924-0439-471F-AAAE-EC3E5C274EA4Q27308965-F1EFA6EE-707E-47BC-A67D-5774754670C9Q27334152-7BAF3872-627F-4D6E-B49A-BE206113EEB9Q27341372-9F2DD9D4-C74F-4D34-A427-13EF27B43E69Q27766337-BB273E65-D480-4F60-BB8C-E5D4158ABFBBQ27939243-C95E30B5-6AEA-45A7-B4F0-7A037B92E1CFQ28142145-87EF44E3-87C2-40FF-939A-F8168F7D7B47Q28144060-EFE324AA-C0FF-499A-81C2-86F5FE87C97EQ28145764-A705FFB7-0FC4-449F-A7ED-1A33BA9C9A10Q28198681-CAE067F4-08B5-48F0-A774-36C9033CA084Q28205608-EA21D6CB-F264-4A54-90B7-1150B079565CQ28267097-B0658449-933E-4BEA-BD55-B339916B5EF5Q28506023-3D28E1C6-6E5F-4814-9234-6AC12FB8C1E6Q28507382-DF237C95-0B6A-49E1-9421-F1A0FFCEDA08Q28564174-7F635E26-05CE-4A97-9A39-A10490A2BDAFQ28585658-259540B9-5083-4F8B-87AA-48CD9EC5D13BQ28591289-FA6DFA74-5622-41C2-81FA-417B66F51012Q28646556-B39E7017-7665-452E-8FA7-EED84D6C0756Q28731285-88FBA094-25CD-4A58-8355-50ACDAC4CCB9Q28752471-CFE4E44F-F330-45DE-93E6-0C8D72D08DB6Q30164937-4E7086C1-292B-481B-B611-00125095F81AQ30167854-050E50B6-21D4-45B3-8BEE-D1F654311B2DQ30495861-039AC823-95C9-42F8-A42F-1F8F9F2364DBQ30499947-CBC0EFCE-68C9-4C9C-B9D3-2A32919A6F27Q30617477-6F12E630-CF49-49D3-A6A6-E2D7B81C5D0EQ33265884-7B422363-2B96-43B0-8283-A301C75C5F31Q33324472-5740B3CA-026A-486D-A2D9-20C2016F4B47Q33327418-41F32FBD-0E24-485F-9422-34694EF237A9Q33469965-F976B2CA-F417-4BBB-82A7-FD6150235A8FQ33585874-D810ABFF-AE47-4376-B3B0-4103362279B5Q33641659-9CA17CC4-EFB9-4436-8B4E-4621C361E520Q33863444-04E3C128-A68E-4870-93F3-9A812F90C09C
P2860
UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
UNC-73 activates the Rac GTPas ...... cone migrations in C. elegans.
@ast
UNC-73 activates the Rac GTPas ...... cone migrations in C. elegans.
@en
type
label
UNC-73 activates the Rac GTPas ...... cone migrations in C. elegans.
@ast
UNC-73 activates the Rac GTPas ...... cone migrations in C. elegans.
@en
prefLabel
UNC-73 activates the Rac GTPas ...... cone migrations in C. elegans.
@ast
UNC-73 activates the Rac GTPas ...... cone migrations in C. elegans.
@en
P2093
P1433
P1476
UNC-73 activates the Rac GTPas ...... cone migrations in C. elegans
@en
P2093
A Ruiz Morales
J Mancillas
S Kulkarni
T J Kubiseski
P304
P356
10.1016/S0092-8674(00)81406-3
P407
P577
1998-03-01T00:00:00Z