Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b - Wikidata - awgldk - TriplyDB

Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b

Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b

http://www.wikidata.org/entity/Q30462065

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Dysregulation and restoration of translational homeostasis in fragile X syndrome Channelopathies and dendritic dysfunction in fragile X syndrome.Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome From FMRP function to potential therapies for fragile X syndrome.Degraded speech sound processing in a rat model of fragile X syndrome Linking neural activity and molecular oscillations in the SCN.Deletion of Fmr1 alters function and synaptic inputs in the auditory brainstem.Failed stabilization for long-term potentiation in the auditory cortex of FMR1 knockout mice Impaired critical period plasticity in primary auditory cortex of fragile X model mice Auditory processing in fragile x syndrome.Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein Potassium channel modulation and auditory processing Gradients and modulation of K(+) channels optimize temporal accuracy in networks of auditory neurons.FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome.Increasing our understanding of human cognition through the study of Fragile X Syndrome.Bidirectional control of BK channel open probability by CAMKII and PKC in medial vestibular nucleus neurons Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.Altered neocortical rhythmic activity states in Fmr1 KO mice are due to enhanced mGluR5 signaling and involve changes in excitatory circuitry Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.Targeted treatments for fragile X syndrome.Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brain stem neurons.Loss of functional A-type potassium channels in the dendrites of CA1 pyramidal neurons from a mouse model of fragile X syndrome.Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models.Fragile X mental retardation protein and synaptic plasticity The translation of translational control by FMRP: therapeutic targets for FXS.Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation.Multifarious Functions of the Fragile X Mental Retardation Protein.The need for new approaches in CNS drug discovery: Why drugs have failed, and what can be done to improve outcomes.Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry.Cellular distribution of the fragile X mental retardation protein in the mouse brain.Intense and specialized dendritic localization of the fragile X mental retardation protein in binaural brainstem neurons: a comparative study in the alligator, chicken, gerbil, and human.Cell-Type Specific Channelopathies in the Prefrontal Cortex of the fmr1-/y Mouse Model of Fragile X Syndrome.Reduced Lateral Inhibition Impairs Olfactory Computations and Behaviors in a Drosophila Model of Fragile X Syndrome.Imbalance of synaptic actin dynamics as a key to the Fragile X syndrome?

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P2860

Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b

http://www.wikidata.org/entity/Q30462065

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

@wuu

name

Fragile X mental retardation p ...... f the potassium channel Kv3.1b

@ast

Fragile X mental retardation p ...... f the potassium channel Kv3.1b

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type

label

Fragile X mental retardation p ...... f the potassium channel Kv3.1b

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Fragile X mental retardation p ...... f the potassium channel Kv3.1b

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prefLabel

Fragile X mental retardation p ...... f the potassium channel Kv3.1b

@ast

Fragile X mental retardation p ...... f the potassium channel Kv3.1b

@en

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JNEUROSCI.1125-10.2010

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Journal of Neuroscience

P1476

Fragile X mental retardation p ...... f the potassium channel Kv3.1b

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P2093

Daniel B Polley

http://www.w3.org/2001/XMLSchema#string

Jack Kronengold

http://www.w3.org/2001/XMLSchema#string

John G Strumbos

http://www.w3.org/2001/XMLSchema#string

Leonard K Kaczmarek

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Maile R Brown

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P2860

FMR1 protein: conserved RNP family domains and selective RNA binding

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

Evidence that fragile X mental retardation protein is a negative regulator of translation

The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts

Localization of two high-threshold potassium channel subunits in the rat central auditory system

Specific and rapid effects of acoustic stimulation on the tonotopic distribution of Kv3.1b potassium channels in the adult rat

Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain

The fragile X mental retardation protein inhibits translation via interacting with mRNA

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10263-10271

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scholarly article

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10.1523/JNEUROSCI.1125-10.2010

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31

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20685971

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3485078

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