A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors.
about
A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic α-Exosite Binding RegionZinc-mediated Allosteric Inhibition of Caspase-6Phosphorylation regulates assembly of the caspase-6 substrate-binding groove.Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage.Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate.High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.The initial substrate-binding site of gamma-secretase is located on presenilin near the active siteDiscovery of novel inhibitors of a disintegrin and metalloprotease 17 (ADAM17) using glycosylated and non-glycosylated substrates.In Silico Design of Novel Anticoagulant Peptides targeting Blood Coagulation Factor VIIa.Using fluorogenic peptide substrates to assay matrix metalloproteinases.Discovery methodology for the development of direct factor VIIa inhibitors.Potent anticoagulant aptamer directed against factor IXa blocks macromolecular substrate interaction.Triple-helical transition state analogues: a new class of selective matrix metalloproteinase inhibitors.Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex.Activity of ADAM17 (a disintegrin and metalloprotease 17) is regulated by its noncatalytic domains and secondary structure of its substrates.Analysis of flavonoid-based pharmacophores that inhibit aggrecanases (ADAMTS-4 and ADAMTS-5) and matrix metalloproteinases through the use of topologically constrained peptide substrates.Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.Mechanisms of macromolecular protease inhibitorsInhibitors of the initiation of coagulation.Protein anticoagulants targeting factor VIIa-tissue factor complex: a comprehensive review.Peptide from the C-terminal domain of tissue inhibitor of matrix metalloproteinases-2 (TIMP-2) inhibits membrane activation of matrix metalloproteinase-2 (MMP-2).Biphenylsulfonacetic acid inhibitors of the human papillomavirus type 6 E1 helicase inhibit ATP hydrolysis by an allosteric mechanism involving tyrosine 486The mechanism of inhibition of antibody-based inhibitors of membrane-type serine protease 1 (MT-SP1).Fusion of two distinct peptide exosite inhibitors of Factor VIIa.Hemextin AB complex, a unique anticoagulant protein complex from Hemachatus haemachatus (African Ringhals cobra) venom that inhibits clot initiation and factor VIIa activity.Substrate conformation modulates aggrecanase (ADAMTS-4) affinity and sequence specificity. Suggestion of a common topological specificity for functionally diverse proteases.
P2860
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P2860
A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A novel exosite on coagulation ...... w class of peptide inhibitors.
@ast
A novel exosite on coagulation ...... w class of peptide inhibitors.
@en
type
label
A novel exosite on coagulation ...... w class of peptide inhibitors.
@ast
A novel exosite on coagulation ...... w class of peptide inhibitors.
@en
prefLabel
A novel exosite on coagulation ...... w class of peptide inhibitors.
@ast
A novel exosite on coagulation ...... w class of peptide inhibitors.
@en
P2093
P356
P1433
P1476
A novel exosite on coagulation ...... w class of peptide inhibitors.
@en
P2093
P304
P356
10.1021/BI010592D
P407
P577
2001-08-01T00:00:00Z