Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
about
The desmosomeDesmosomes in acquired diseasePreclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgarisMechanistic basis of desmosome-targeted diseasesPemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptorPeptides Targeting the Desmoglein 3 Adhesive Interface Prevent Autoantibody-induced Acantholysis in Pemphigus.Desmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus.Adducin is required for desmosomal cohesion in keratinocytes.Mechanisms of Autoantibody-Induced Pathology.The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.Plakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.p38 MAPK activation is downstream of the loss of intercellular adhesion in pemphigus vulgaris.Signaling dependent and independent mechanisms in pemphigus vulgaris blister formationDesmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion.Desmoglein 2 mutant mice develop cardiac fibrosis and dilation.Structure, function, and regulation of desmosomes.The extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?Nanorobotic investigation identifies novel visual, structural and functional correlates of autoimmune pathology in a blistering skin disease model.Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blisteringDesmosomes: new perpetrators in tumour suppressionInvolvement of the apoptotic mechanism in pemphigus foliaceus autoimmune injury of the skin.Setting the target for pemphigus vulgaris therapy.Intercellular junction assembly, dynamics, and homeostasis.Desmosomes: adhesive strength and signalling in health and disease.Desmosomal cadherins and signaling: lessons from autoimmune disease.Desmosomes and extradesmosomal adhesive signaling contacts in pemphigus.150(th) anniversary series: Desmosomes and autoimmune disease, perspective of dynamic desmosome remodeling and its impairments in pemphigus.Immune response in pemphigus and beyond: progresses and emerging concepts.Mechanisms of Disease: Pemphigus and Bullous Pemphigoid.Desmoglein 2 compensates for desmoglein 3 but does not control cell adhesion via regulation of p38 mitogen-activated protein kinase in keratinocytes.Pemphigus, a pathomechanism of acantholysis.MAPKAP kinase 2 (MK2)-dependent and -independent models of blister formation in pemphigus vulgaris.Protective endogenous cyclic adenosine 5'-monophosphate signaling triggered by pemphigus autoantibodies.Actin reorganization contributes to loss of cell adhesion in pemphigus vulgaris.Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3Apoptosis is not required for acantholysis in pemphigus vulgaris.Experimental human cell and tissue models of pemphigus.Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering.Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus.Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity.
P2860
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P2860
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
@ast
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
@en
type
label
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
@ast
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
@en
prefLabel
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
@ast
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
@en
P1476
Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.
@en
P2093
Detlev Drenckhahn
Wolfgang-Moritz Heupel
P304
P356
10.4049/JIMMUNOL.181.3.1825
P407
P577
2008-08-01T00:00:00Z