Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3 - Wikidata - awgldk - TriplyDB

Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3

Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3

http://www.wikidata.org/entity/Q39723951

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Desmosomes in acquired disease Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris Desmosome assembly and disassembly are membrane raft-dependent Mechanisms of Autoantibody-Induced Pathology.Signaling dependent and independent mechanisms in pemphigus vulgaris blister formation Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion.Desmoglein as a target in skin disease and beyond.FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes.Structure, function, and regulation of desmosomes.Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface.The C-terminal unique region of desmoglein 2 inhibits its internalization via tail-tail interactions.Super-Resolution Microscopy Reveals Altered Desmosomal Protein Organization in Tissue from Patients with Pemphigus Vulgaris.Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes Pemphigus autoimmunity: hypotheses and realities.Cell-cell connectivity: desmosomes and disease.Structural and functional diversity of desmosomes.Desmosomes and extradesmosomal adhesive signaling contacts in pemphigus.150(th) anniversary series: Desmosomes and autoimmune disease, perspective of dynamic desmosome remodeling and its impairments in pemphigus.Plakophilin-1 protects keratinocytes from pemphigus vulgaris IgG by forming calcium-independent desmosomes 150th Anniversary Series: Desmosomes and the Hallmarks of Cancer.Mechanisms of Disease: Pemphigus and Bullous Pemphigoid.The Bacterial Enzyme IdeS Cleaves the IgG-Type of B Cell Receptor (BCR), Abolishes BCR-Mediated Cell Signaling, and Inhibits Memory B Cell Activation.Pemphigus vulgaris autoimmune globulin induces Src-dependent tyrosine-phosphorylation of plakophilin 3 and its detachment from desmoglein 3.Desmosomes and Intermediate Filaments: Their Consequences for Tissue Mechanics.Pemphigus, a pathomechanism of acantholysis.Desmosomes in the testis: Moving into an unchartered territory.Differential downregulation of e-cadherin and desmoglein by epidermal growth factor.Pemphigus: a Comprehensive Review on Pathogenesis, Clinical Presentation and Novel Therapeutic Approaches.Pemphigus-A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms.Particle Bombardment of Ex Vivo Skin to Deliver DNA and Express Proteins.A New Classification System for IgG4 Autoantibodies.Atomic Force Microscopy Provides New Mechanistic Insights into the Pathogenesis of Pemphigus.Connexins: Synthesis, Post-Translational Modifications, and Trafficking in Health and Disease.Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus.Autoantibody Signaling in Pemphigus Vulgaris: Development of an Integrated Model.Keratin Retraction and Desmoglein3 Internalization Independently Contribute to Autoantibody-Induced Cell Dissociation in Pemphigus Vulgaris.Immunoadsorption of Desmoglein-3-Specific IgG Abolishes the Blister-Inducing Capacity of Pemphigus Vulgaris IgG in Neonatal Mice

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P2860

Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3

http://www.wikidata.org/entity/Q39723951

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Desmosome disassembly in respo ...... y expression of exogenous Dsg3

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Desmosome disassembly in respo ...... expression of exogenous Dsg3.

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Desmosome disassembly in respo ...... y expression of exogenous Dsg3

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Desmosome disassembly in respo ...... expression of exogenous Dsg3.

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Desmosome disassembly in respo ...... y expression of exogenous Dsg3

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Desmosome disassembly in respo ...... expression of exogenous Dsg3.

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Journal of Investigative Dermatology

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Desmosome disassembly in respo ...... y expression of exogenous Dsg3

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Andrew P Kowalczyk

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Dana K Tucker

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Emmanuella Delva

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Jean M Jennings

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Margaret D Kottke

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Masataka Saito

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Yasushi Hanakawa

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P2860

Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly

Desmosome structure, composition and function

Mechanisms of disease: molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy

Plakins in development and disease

Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism

Pemphigus vulgaris IgG directly inhibit desmoglein 3-mediated transinteraction.

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin.

Mechanisms of desmosome assembly and disassembly.

p38MAPK inhibition prevents disease in pemphigus vulgaris mice.

Cadherins as modulators of cellular phenotype.

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10.1038/JID.2010.389

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3

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131

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Masayuki Amagai

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49685537

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21160493

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3235416

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