Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching. - Wikidata - awgldk - TriplyDB

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

http://www.wikidata.org/entity/Q33880995

about

Immunoglobulin class switch recombination is impaired in Atm-deficient mice XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure RNA Exosome Regulates AID DNA Mutator Activity in the B Cell Genome AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.Rat L (long interspersed repeated DNA) elements contain guanine-rich homopurine sequences that induce unpairing of contiguous duplex DNA Switch recombination and somatic hypermutation are controlled by the heavy chain 3' enhancer region.Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70 Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences.The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination Roles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombination Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse.Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5 Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination.De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination.DNA sequences at immunoglobulin switch region recombination sites AID to overcome the limitations of genomic information by introducing somatic DNA alterations.Nongenic, bidirectional transcription precedes and may promote developmental DNA deletion in Tetrahymena thermophila.Alpha2p controls donor preference during mating type interconversion in yeast by inactivating a recombinational enhancer of chromosome III Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation.Strong transcriptional activation of translocated c-myc genes occurs without a strong nearby enhancer or promoter T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells.Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations.Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.Molecular analysis of the induction of immunoglobulin E synthesis in human B cells by interleukin 4 and engagement of CD40 antigen.Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications.Active lambda and kappa antibody gene rearrangement in Abelson murine leukemia virus-transformed pre-B cell lines.Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells.Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells.Interleukin 5 induces S mu-S gamma 1 DNA rearrangement in B cells activated with dextran-anti-IgD antibodies and interleukin 4: a three component model for Ig class switching.Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation.Evidence for class-specific factors in immunoglobulin isotype switching Quantitative regulation of class switch recombination by switch region transcription.Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase.Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes.Sgamma3 switch sequences function in place of endogenous Sgamma1 to mediate antibody class switching

P2860

Q24647660-7BA475C5-47FE-4E67-9CE6-791348363164 Q24672147-048603DC-97CD-44D6-899C-7F9E807FF5D6 Q28087424-AED99BCD-D28F-48F3-8AC0-CF46A3F741BA Q28366125-257417CD-B9BA-4087-83F3-8747B76C4E8F Q33563951-68DB6E6B-FA3A-4F47-8904-CF89626515F9 Q33582163-50449828-7C0D-4377-912B-4E3A65F4F6A1 Q33591104-E18AD885-ACC0-44E2-9A54-B49893AEFD25 Q33656152-4F319D4E-605D-4993-BAD7-29DC55344BFF Q33733981-B7B63B7B-EA8C-4844-B5BD-F762D9080F03 Q33950143-1A728C02-3190-4341-8C04-063DE986F26A Q34115234-EA953F4D-5DCA-4014-BFEE-90B27655FF11 Q34242737-15B3A3B5-6637-4E20-8BAA-925D79F5CCA9 Q34263084-CFCD007B-62CC-4A26-B9B0-87A0ABF6CFEC Q34308191-02C935E5-1B98-40FB-BB21-8917683C4433 Q34313264-9EC4D990-390D-4543-909A-E15338196EE5 Q34357060-1AD32E90-7CA8-4248-942D-7B9B65389532 Q34438355-41B34D35-6D4A-41F2-9019-4E83899CD74A Q34807643-755E1941-D083-4A0A-A589-0E1AFD6D1C75 Q34963864-7FF9E193-C604-4014-995F-ED66F4AE137B Q35068183-87D0155A-8A0F-42D7-905F-5B78EA4F3EBF Q35110180-AE2EA578-92EF-44A7-98DC-FD0951D65BE7 Q35187500-B611DFAF-58CB-4253-8E1C-86BBE6C7D6BA Q35585876-97787819-2FDD-4074-A4ED-1C65148F783F Q35939969-A39A0EE4-E4D2-42F4-9AFF-FAC2E67AFAAA Q35955998-FA12E2CD-1912-4E0E-8143-77ACFF2DA8AA Q35992414-A54C43A8-FE1D-4331-A591-A8A228B4E844 Q36116985-82A7C157-BB21-4111-A682-6F1C846C10E9 Q36230750-632928E2-4D36-497F-AFD3-B209BF15003E Q36316915-A5C75353-FE41-4BCB-A269-D21BF1FD16B4 Q36352706-41FDD18A-B12F-4B31-AEE4-3123640948AC Q36355701-DBC21F23-EDC4-41DC-ABA2-86F5E24FB8D9 Q36361621-78CD3082-0B37-4A7B-912A-FABC15667422 Q36362532-FA2290E4-2D1F-454F-B53D-2A5B9E17757A Q36366690-3125C608-B55F-4E19-849C-894DEC4ED6F4 Q36368414-3F2431D6-F873-4439-8AD0-5D5330FA6464 Q36369428-2EA7E3BE-2288-4330-8104-28FF90A5822E Q36399510-9EA14D0D-E13F-4A1D-97F1-FFE76FEB1F3D Q36404262-CED5CFEB-56D1-4434-A4DB-5E32A0A66E14 Q36714537-4D541AEC-7061-45D6-9164-9FE8876D6BCD Q36742253-767E145C-14BA-4C7E-B2D8-1DAC6202A24D

P2860

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

http://www.wikidata.org/entity/Q33880995

description

1986 nî lūn-bûn

@nan

1986 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1986 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1986年の論文

@ja

1986年論文

@yue

1986年論文

@zh-hant

1986年論文

@zh-hk

1986年論文

@zh-mo

1986年論文

@zh-tw

1986年论文

@wuu

name

Secondary genomic rearrangemen ...... and directed class switching.

@ast

Secondary genomic rearrangemen ...... and directed class switching.

@en

type

label

Secondary genomic rearrangemen ...... and directed class switching.

@ast

Secondary genomic rearrangemen ...... and directed class switching.

@en

prefLabel

Secondary genomic rearrangemen ...... and directed class switching.

@ast

Secondary genomic rearrangemen ...... and directed class switching.

@en

P1433

Q33880995-D29FE3A8-E1B7-4197-922F-7C1830C5FC95

P1476

Q33880995-BF531918-0B94-41B9-8060-215E55F7C28C

P2093

Q33880995-1F64D2BA-B476-40BC-BC3A-4106A6296E34

Q33880995-63E8D17D-04D6-46BD-9C63-AB8C3D543CF7

Q33880995-8CE963C1-7316-4C1B-B81E-D27278700536

Q33880995-91340794-0C7C-45FF-AA1D-CBF5CE558D40

Q33880995-DB16C1F2-2B5B-46B4-913C-02FFC404BD58

Q33880995-E3C6CBF2-ECA6-47CE-AC60-77E8EBBD9A6B

P2860

Q33880995-08561073-8276-4EE1-9E42-A91B3CDFD4CC

Q33880995-0B836E2C-BB5C-4267-BC51-E6FF8A4B09A1

Q33880995-0CFDB233-8DAA-4910-B8C2-342EB0A5A3C8

Q33880995-0DE7FF8B-67BD-405C-AB3D-343DC8939F82

Q33880995-10BCD97A-3941-4602-9808-CAD3FE97C253

Q33880995-13A81659-7594-478F-BC1A-0E0CCAACCE96

Q33880995-159CD3B0-F1A5-4362-BA64-9B4FAB7F6991

Q33880995-259FE887-A649-4A5F-87D7-899804341479

Q33880995-36F859D2-4837-44E1-B781-42083B3C6D39

Q33880995-405F67CF-3F0A-4D5A-9C03-3312BCCF45BE

P304

Q33880995-42090BEA-2601-445A-8CBE-CA86E4A564D4

P31

Q33880995-52CC47D6-8559-4FFD-9FF9-A686C15F6487

P407

Q33880995-AEB0B9B4-7D3E-478F-9465-EBE029CBEC5A

P433

Q33880995-EDA9664E-6675-443D-9D4F-33B9E4340A6F

P478

Q33880995-31E5D93F-F20C-4078-B77E-76B68EA45122

P577

Q33880995-D8AB4E14-B625-4229-B46E-313B4C4AFA2F

P698

Q33880995-2DF684B5-7348-42FB-9629-46D4CCB38067

P932

Q33880995-B6DCA6C8-8EFB-4159-BA96-3663381FC7BA

P1433

The EMBO Journal

P1476

Secondary genomic rearrangemen ...... and directed class switching.

@en

P2093

F W Alt

http://www.w3.org/2001/XMLSchema#string

G D Yancopoulos

http://www.w3.org/2001/XMLSchema#string

K A Zimmerman

http://www.w3.org/2001/XMLSchema#string

N Rosenberg

http://www.w3.org/2001/XMLSchema#string

R A DePinho

http://www.w3.org/2001/XMLSchema#string

S G Lutzker

http://www.w3.org/2001/XMLSchema#string

P2860

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase

Long identical repeats in the mouse gamma 2b switch region and their implications for the mechanism of class switching.

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain.

Extended Watson integrals for the cubic lattices.

Nucleotide sequence definition of a major human repeated DNA, the Hind III 1.9 kb family

A switch region inversion contributes to the aberrant rearrangement of a mu immunoglobulin heavy chain gene in MPC-11 cells.

Activation of a novel KpnI transcript by downstream integration of a human T-lymphotropic virus type I provirus.

Ordered rearrangement of immunoglobulin heavy chain variable region segments

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.

P304

3259-3266

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P577

1986-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

3028778

http://www.w3.org/2001/XMLSchema#string

P932

1167320

http://www.w3.org/2001/XMLSchema#string