Negative regulation of activation-induced cytidine deaminase in B cells - Wikidata - awgldk - TriplyDB

Negative regulation of activation-induced cytidine deaminase in B cells

Negative regulation of activation-induced cytidine deaminase in B cells

http://www.wikidata.org/entity/Q34479651

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Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase First AID (activation-induced cytidine deaminase) is needed to produce high affinity isotype-switched antibodies Altered pattern of immunoglobulin hypermutation in mice deficient in Slip-GC protein T cells contain an RNase-insensitive inhibitor of APOBEC3G deaminase activity.AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.Functions and regulation of the APOBEC family of proteins Generation and repair of AID-initiated DNA lesions in B lymphocytes.Origin of chromosomal translocations in lymphoid cancer.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.AID and somatic hypermutation.Activation-induced cytidine deaminase accelerates clonal evolution in BCR-ABL1-driven B-cell lineage acute lymphoblastic leukemia.Lysine residue at position 22 of the AID protein regulates its class switch activity.Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE.AID-initiated DNA lesions are differentially processed in distinct B cell populations.Targeting of somatic hypermutation.Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer.Activation-induced cytidine deaminase in B cells of hepatits C virus-related cryoglobulinaemic vasculitis.Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF AID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway.53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma.Estrogen directly activates AID transcription and function Decreased mutation frequencies among immunoglobulin G variable region genes during viremic HIV-1 infection.Activation-induced cytidine deaminase and aberrant germinal center selection in the development of humoral autoimmunities MicroRNAs and lymphomagenesis: a functional review.Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney Epigenetic function of activation-induced cytidine deaminase and its link to lymphomagenesis The biology of aging and lymphoma: a complex interplay.The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas.Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes.AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model.MicroRNA-181b regulates endotoxin tolerance by targeting IL-6 in macrophage RAW264.7 cells.Activation-induced cytidine deaminase prevents pro-B cell acute lymphoblastic leukemia by functioning as a negative regulator in Rag1 deficient pro-B cells.A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.Efficient Induction of Ig Gene Hypermutation in Ex Vivo-Activated Primary B Cells.Identification of a specific domain required for dimerization of activation-induced cytidine deaminase

P2860

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Negative regulation of activation-induced cytidine deaminase in B cells

http://www.wikidata.org/entity/Q34479651

description

2006 nî lūn-bûn

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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի փետրվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Negative regulation of activation-induced cytidine deaminase in B cells

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Negative regulation of activation-induced cytidine deaminase in B cells

@en

Negative regulation of activation-induced cytidine deaminase in B cells

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type

label

Negative regulation of activation-induced cytidine deaminase in B cells

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Negative regulation of activation-induced cytidine deaminase in B cells

@en

Negative regulation of activation-induced cytidine deaminase in B cells

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prefLabel

Negative regulation of activation-induced cytidine deaminase in B cells

@ast

Negative regulation of activation-induced cytidine deaminase in B cells

@en

Negative regulation of activation-induced cytidine deaminase in B cells

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PNAS.0510970103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Negative regulation of activation-induced cytidine deaminase in B cells

@en

P2093

Hitoshi Nagaoka

http://www.w3.org/2001/XMLSchema#string

Kazuo Kinoshita

http://www.w3.org/2001/XMLSchema#string

Shuichi Yamada

http://www.w3.org/2001/XMLSchema#string

Taro Muto

http://www.w3.org/2001/XMLSchema#string

P2860

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

Somatic hypermutation of the AID transgene in B and non-B cells

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma.

Genome-wide somatic hypermutation.

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

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2752-2757

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scholarly article

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8

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103

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Yoshimasa Tanaka

Masamichi Muramatsu

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2006-02-13T00:00:00Z

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7300018

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16477013

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1413812

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