The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism. - Wikidata - awgldk - TriplyDB

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism.

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism.

http://www.wikidata.org/entity/Q33726100

about

Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase Splicing factor SRSF6 promotes hyperplasia of sensitized skin Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies Pyruvate Kinase M2: A Potential Target for Regulating Inflammation Pyruvate kinase: Function, regulation and role in cancer Splicing Regulation: A Molecular Device to Enhance Cancer Cell Adaptation Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer Misregulation of pre-mRNA alternative splicing in cancer Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy Adipose tissue dysfunction and its effects on tumor metabolism The role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progression Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer.A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay.Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression Characterization of a novel posttranslational modification in polypyrimidine tract-binding proteins by SUMO1.Living or dying by RNA processing: caspase expression in NSCLC.A cell engineering strategy to enhance the safety of stem cell therapies.Quaking I controls a unique cytoplasmic pathway that regulates alternative splicing of myelin-associated glycoprotein Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells.Heterogeneous ribonucleoprotein C displays a repressor activity mediated by T-cell intracellular antigen-1-related/like protein to modulate Fas exon 6 splicing through a mechanism involving Hu antigen R.Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition.IL-6-induced enhancement of c-Myc translation in multiple myeloma cells: critical role of cytoplasmic localization of the rna-binding protein hnRNP A1.Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question Mechanisms and Regulation of Alternative Pre-mRNA Splicing Co-regulation of alternative splicing by diverse splicing factors in Caenorhabditis elegans CC3/TIP30 regulates metabolic adaptation of tumor cells to glucose limitation Functional consequences of developmentally regulated alternative splicing.Polypyrimidine tract binding protein-1 (PTB1) is a determinant of the tissue and host tropism of a human rhinovirus/poliovirus chimera PV1(RIPO).Drosophila Hephaestus/polypyrimidine tract binding protein is required for dorso-ventral patterning and regulation of signalling between the germline and soma.PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity in Latvians, Lithuanians and Taiwanese Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation Antisense Modulation of RNA Processing as a Therapeutic Approach in Cancer Therapy.

P2860

Q24310494-CFD08935-F316-4449-9C63-744095E8ED73 Q24321623-6C508396-6619-4A85-84A1-967CFB0CFE7B Q24603549-921FAB06-E1D4-4198-8D3A-9BA7DA11B696 Q24628801-F76B46A3-5D34-4B79-B468-E098F6EEECDA Q26752535-B51B39A5-D56E-4749-99AB-41F5A1BE8981 Q26798084-7F04FC1A-8017-4B0C-9967-0DE8EB1D4C9B Q26798148-300756BB-568A-49D0-B36E-31FEA708805E Q27001635-42D8ACDF-92E1-49B0-84AF-41FEE77CDA46 Q27007114-E2521D48-C4BB-4446-8856-7DF7E919FE78 Q27671695-50F06A75-2457-4565-8DA7-24117F055B52 Q27673508-BDEBD06F-F903-4463-BF1E-C4CF34A5D981 Q28080748-5CBCD788-BFFB-48BA-98A7-88BD0CD23CB7 Q28083838-B7677D54-408F-4C40-9B4B-CFBAA6A35300 Q28297381-EFD04DD5-176D-4DBF-B79E-1F2E0DF042DE Q28547155-50731240-5223-4068-86E3-353E9B428586 Q30497879-CBB4AEDD-F248-4F3C-8582-1599D54E45D8 Q32183014-41BC9B24-4ABA-4C85-88FF-E997163E5F1C Q33718674-E2ED0DC4-C925-4312-AE58-BDD9DADB5031 Q33739006-E640F781-D282-46F8-B974-053A62FD8663 Q34136997-A810CB49-F728-46A8-BC64-20726D2EEA03 Q34180088-225A178B-7AEF-4ACD-9BF9-46D076BCBD3E Q34245513-8B5097CC-7DC2-4946-9B4A-71C14A43EEE2 Q34254731-5003C970-2E22-4CB7-8391-1E733483B9A4 Q34279119-3C156DB7-A06C-4CB7-B2DC-1716892E4672 Q34338923-E576C4F8-CB46-494D-AF26-D7013D24C08A Q34377342-A59DA247-BD0E-4EF8-A950-7370D562F72A Q34387675-9DF09866-F6FE-46D6-B018-3A81C52A30C3 Q34401415-0A46A93E-2E9A-48CE-A3EF-A777EA2C747D Q34442342-A7507C6E-6D74-4089-B878-AA8A8009C3CA Q34452704-500ADBCB-AB54-4FD8-814A-357389F56BC9 Q34459681-A7AFCE86-9DBC-4D59-A5D8-F317235A7411 Q34467642-A9AFA7A4-68D7-4095-87EC-36F7AAE32C12 Q34513751-DBF7D0A3-8CC3-48A2-B715-5D5CF910E347 Q34619824-F44D47EB-CDA5-4AA8-A3CF-2132022CE75A Q34632366-DC54DA64-78B3-4002-BDE4-345637C676BD Q34674160-640B70CA-0A29-4EA5-993A-B992E9B1BF4C Q34874964-E8FD157B-DE78-4E17-ABF3-01CA36D34FD4 Q34880720-CA5A0D26-348C-4458-925E-042BFA3B0188 Q34898927-94683B7A-7791-4E08-9099-256C2C3C7415 Q34911031-B5AAC6F1-0A76-48FD-B666-600C2A6D3FA6

P2860

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism.

http://www.wikidata.org/entity/Q33726100

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The alternative splicing repre ...... xpression and cell metabolism.

@ast

The alternative splicing repre ...... xpression and cell metabolism.

@en

type

label

The alternative splicing repre ...... xpression and cell metabolism.

@ast

The alternative splicing repre ...... xpression and cell metabolism.

@en

prefLabel

The alternative splicing repre ...... xpression and cell metabolism.

@ast

The alternative splicing repre ...... xpression and cell metabolism.

@en

P1433

Q33726100-67860433-FB16-4237-9DD6-525BCAEDF404

P1476

Q33726100-15450344-979D-47CF-A154-8141C4B9915F

P2093

Q33726100-533D84E8-1C14-40D6-8941-68902F58B716

Q33726100-7EF79D6F-DE36-46D4-A624-0B761580B0E1

Q33726100-8B7C7527-4A4E-49AD-8167-42653BAA45B7

Q33726100-B76B021E-119F-49D6-9186-DA840852CB08

P2860

Q33726100-15D276A0-4C7C-4BB1-B38A-82C8E58B1F0C

Q33726100-178D60F8-BB6B-48AA-A2DB-AF58DEBA15F3

Q33726100-210E61A1-F4A3-41FF-B127-F2A6E0700734

Q33726100-2EB710C4-0CBF-4568-97A0-636D060AE4EE

Q33726100-4322AFDB-82BF-4132-91C8-3136EDB8BD4D

Q33726100-46AC042F-9781-41FE-81FA-03C795E2F481

Q33726100-48DE2F45-6966-4B7B-865D-C0401A0B4BEF

Q33726100-4FDBE486-433E-478C-994F-9D029135DAA2

Q33726100-53CCDC03-F3E7-4AB4-88A2-9BB14D104D39

Q33726100-5AF08477-AC49-4AF0-96D2-3C849BA2E129

P304

Q33726100-C19DED58-E88B-4D6F-9952-6D59F6A3EB73

P31

Q33726100-2A9561DD-BF59-47C4-A660-3AD6BF39C396

P356

Q33726100-9EEF52A9-7C63-4FC0-B484-FC073FCBB5D4

P433

Q33726100-59157904-FE1D-4CC0-9AB1-736A322F9611

P478

Q33726100-979CC30A-B162-4E3F-A473-EE18A6DD2F81

P50

Q33726100-C3775FF7-BA7A-43CC-BAA2-782B8625FBD2

Q33726100-DEF4084B-DDC7-413E-80BF-34AC0A7252C8

P577

Q33726100-CFB2A2F3-B15E-488B-B30D-E764C7082CF7

P5875

Q33726100-D4EE873B-A17D-4350-AA16-B140D7F9897D

P698

Q33726100-F61FB841-CF9D-4F82-A41F-B8F390FC3230

P932

Q33726100-55ACC0A6-9BAB-49AD-8039-D1134657CB7F

P356

PNAS.0914845107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

The alternative splicing repre ...... xpression and cell metabolism.

@en

P2093

Cynthia V Clower

http://www.w3.org/2001/XMLSchema#string

Deblina Chatterjee

http://www.w3.org/2001/XMLSchema#string

Matthew G Vander Heiden

http://www.w3.org/2001/XMLSchema#string

Zhenxun Wang

http://www.w3.org/2001/XMLSchema#string

P2860

The dynamic organization of the perinucleolar compartment in the cell nucleus

Pyruvate kinase M2 is a phosphotyrosine-binding protein

The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

Mechanisms of alternative pre-messenger RNA splicing

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

Pyruvate kinase type M2 and its role in tumor growth and spreading

Phosphofructokinase 2: the enzyme that forms fructose 2,6-bisphosphate from fructose 6-phosphate and ATP

Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

P304

1894-1899

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0914845107

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P50

Lewis C. Cantley

Adrian Robert Krainer

P577

2010-01-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41408687

http://www.w3.org/2001/XMLSchema#string

P698

20133837

http://www.w3.org/2001/XMLSchema#string

P932

2838216

http://www.w3.org/2001/XMLSchema#string