Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria. - Wikidata - awgldk - TriplyDB

Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

http://www.wikidata.org/entity/Q33735624

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The maintenance of mitochondrial DNA integrity--critical analysis and update Mitochondrial DNA damage and its consequences for mitochondrial gene expression Repair of persistent strand breaks in the mitochondrial genome Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.DNA damage related crosstalk between the nucleus and mitochondria.Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).Poisoning of mitochondrial topoisomerase I by lamellarin D Trypanosoma cruzi gene expression in response to gamma radiation.DNA repair deficiency in neurodegeneration.Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity.Structure and function of the DNA ligases encoded by the mammalian LIG3 gene.Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1).Neurological disorders associated with DNA strand-break processing enzymes.DNA repair mechanisms in dividing and non-dividing cells.Aprataxin localizes to mitochondria and preserves mitochondrial function HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice.Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitors Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genome.Disconnecting XRCC1 and DNA ligase III Exercise Capacity and Response to Training Quantitative Trait Loci in a NZW X 129S1 Intercross and Combined Cross Analysis of Inbred Mouse Strains.Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.A novel diagnostic tool reveals mitochondrial pathology in human diseases and aging TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.Base excision repair in the mammalian brain: implication for age related neurodegeneration Mitochondrial-associated metabolic disorders: foundations, pathologies and recent progress.Epigenetic and genetic inactivation of tyrosyl-DNA-phosphodiesterase 1 (TDP1) in human lung cancer cells from the NCI-60 panel Consensus paper: pathological mechanisms underlying neurodegeneration in spinocerebellar ataxias.PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage.To live or to die: a matter of processing damaged DNA termini in neurons.Oxidative genome damage and its repair in neurodegenerative diseases: function of transition metals as a double-edged sword.Oxidized base damage and single-strand break repair in mammalian genomes: role of disordered regions and posttranslational modifications in early enzymes.The role of TDP1 and APTX in mitochondrial DNA repair.Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.Protecting the mitochondrial powerhouse.Chemical Incorporation of Chain-Terminating Nucleoside Analogs as 3'-Blocking DNA Damage and Their Removal by Human ERCC1-XPF Endonuclease.The role of DNA base excision repair in brain homeostasis and disease.TDP1 is critical for the repair of DNA breaks induced by sapacitabine, a nucleoside also targeting ATM- and BRCA-deficient tumors.Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells.

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P2860

Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

http://www.wikidata.org/entity/Q33735624

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

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Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

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type

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Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

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Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

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Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

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Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

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PNAS.1009814107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria.

@en

P2093

Benu Brata Das

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Kasthuraiah Maddali

http://www.w3.org/2001/XMLSchema#string

Thomas S Dexheimer

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P2860

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

DNA T OPOISOMERASES : Structure, Function, and Mechanism

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1

Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?

Identification and characterization of mitochondrial targeting sequence of human apurinic/apyrimidinic endonuclease 1

Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks

The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily

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19790-19795

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scholarly article

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10.1073/PNAS.1009814107

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46

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107

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2010-11-01T00:00:00Z

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21041670

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2993338

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