Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
about
Regulation of p53 stability and function by the deubiquitinating enzyme USP42NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapyAMF1 (GPS2) modulates p53 transactivationRegulation of p53 function and stability by phosphorylationThe C terminus of p53 family proteins is a cell fate determinantPERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 familyA ribonucleotide reductase gene is a transcriptional target of p53 and p73EGF-mediated regulation of IGFBP-3 determines esophageal epithelial cellular response to IGF-IASPP [corrected] and cancerActivation and activities of the p53 tumour suppressor proteinThe miR-644a/CTBP1/p53 axis suppresses drug resistance by simultaneous inhibition of cell survival and epithelial-mesenchymal transition in breast cancerCHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancerThe C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivoAntagonistic pleiotropy and p53.Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library.The p53 pathway and apoptosis.mdm2: a bridge over the two tumour suppressors, p53 and Rb.AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma.p53 mediates apoptotic crisis in primary Abelson virus-transformed pre-B cells.Concerted regulation of wild-type p53 nuclear accumulation and activation by S100B and calcium-dependent protein kinase C.Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.Tumor suppressor protein p53 recruits human Sin3B/HDAC1 complex for down-regulation of its target promoters in response to genotoxic stress.p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.The role of mutant p53 in human cancer.Nuclear and mitochondrial apoptotic pathways of p53.Activation of various downstream signaling molecules by IGFBP-3.Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes.The genomic landscape of TP53 and p53 annotated high grade ovarian serous carcinomas from a defined founder population associated with patient outcome.The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes.Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses.Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.The tumor suppressor p53 inhibits Net, an effector of Ras/extracellular signal-regulated kinase signalingLow expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer.Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice.Some p53-binding proteins that can function as arbiters of life and death.Anchorless keratinocyte survival: an emerging pathogenic mechanism for squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells.Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis.Codon 104 variation of p53 gene provides adaptive apoptotic responses to extreme environments in mammals of the Tibet plateau.
P2860
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P2860
Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Characterization of structural ...... osis but not cell cycle arrest
@ast
Characterization of structural ...... osis but not cell cycle arrest
@en
type
label
Characterization of structural ...... osis but not cell cycle arrest
@ast
Characterization of structural ...... osis but not cell cycle arrest
@en
prefLabel
Characterization of structural ...... osis but not cell cycle arrest
@ast
Characterization of structural ...... osis but not cell cycle arrest
@en
P2860
P356
P1476
Characterization of structural ...... osis but not cell cycle arrest
@en
P2093
K H Vousden
P2860
P304
P356
10.1128/MCB.18.7.3692
P407
P50
P577
1998-07-01T00:00:00Z