Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
about
An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathwayHuman mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibioticsIdentification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanismsCrystal structure of type II peptide deformylase from Staphylococcus aureusUnderstanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpartEukaryotic peptide deformylases. Nuclear-encoded and chloroplast-targeted enzymes in ArabidopsisLigand-induced changes in the structure and dynamics of Escherichia coli peptide deformylasePeptide deformylase as a target for new generation, broad spectrum antimicrobial agents.Peptide deformylase: a target for novel antibiotics?Control of protein life-span by N-terminal methionine excisionThe crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms.Parasite plastids: maintenance and functionsStructure-Based Drug Design of Small Molecule Peptide Deformylase Inhibitors to Treat Cancer.Peptide deformylase--a promising therapeutic target for tuberculosis and antibacterial drug discovery.Challenges and opportunities in developing novel drugs for TB.Novel antimalarial drug targets: hope for new antimalarial drugs.Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: a new approach to antimicrobial chemotherapy.Ligand and Structure-Based Approaches for the Identification of Peptide Deformylase Inhibitors as Antibacterial Drugs.Type 3 peptide deformylases are required for oxidative phosphorylation in Trypanosoma brucei.
P2860
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P2860
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
@ast
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
@en
type
label
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
@ast
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
@en
prefLabel
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
@ast
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
@en
P1433
P1476
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
@en
P2093
P304
P356
10.1016/S0169-4758(99)01627-0
P577
2000-04-01T00:00:00Z