Apoptotic threshold is lowered by p53 transactivation of caspase-6
about
The transcription factor p53: not a repressor, solely an activatorAberrant expression of the transcription factors snail and slug alters the response to genotoxic stressHow cells switch HIPK2 on and offHOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategiesMLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencingInhibitory Mechanism of Caspase-6 Phosphorylation Revealed by Crystal Structures, Molecular Dynamics Simulations, and Biochemical AssaysBID regulation by p53 contributes to chemosensitivityModeling a snap-action, variable-delay switch controlling extrinsic cell deathTargeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness.Modeling the role of p53 pulses in DNA damage- induced cell death decision.Bleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells.Identification of two novel functional p53 responsive elements in the herpes simplex virus-1 genome.Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis.Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genesInflammation-induced tumorigenesis in mouse colon is caspase-6 independent.A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1.Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo.Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations.Overexpressed DNA polymerase iota regulated by JNK/c-Jun contributes to hypermutagenesis in bladder cancer.Expression and activation of caspase-6 in human fetal and adult tissuesIdentification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe.p53 downstream targets and chemosensitivity.P53 and radiation responses.The role of p53 in chemosensitivity and radiosensitivity.Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling.Apoptosis and colorectal cancer.A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion.Profiling of Signaling Proteins in Penumbra After Focal Photothrombotic Infarct in the Rat Brain Cortex.Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9Silver nanoparticles of Albizia adianthifolia: the induction of apoptosis in human lung carcinoma cell lineN-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis.Caspase-6 as a novel early target in the treatment of Alzheimer's disease.Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy.The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism.Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.Major apoptotic mechanisms and genes involved in apoptosis.HIPK2 modification code for cell death and survival.ZBP-89 reduces the cell death threshold in hepatocellular carcinoma cells by increasing caspase-6 and S phase cell cycle arrest.
P2860
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P2860
Apoptotic threshold is lowered by p53 transactivation of caspase-6
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@ast
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@en
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@nl
type
label
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@ast
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@en
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@nl
prefLabel
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@ast
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@en
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@nl
P2860
P356
P1476
Apoptotic threshold is lowered by p53 transactivation of caspase-6
@en
P2093
Timothy K MacLachlan
P2860
P304
P356
10.1073/PNAS.132241599
P407
P577
2002-06-27T00:00:00Z