Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress. - Wikidata - awgldk - TriplyDB

Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress.

Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress.

http://www.wikidata.org/entity/Q34042602

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Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity and disease Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity Functional roles of protein nitration in acute and chronic liver diseases Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential Alcoholic liver disease: a synopsis of the Charles Lieber's Memorial Symposia 2009-2012.Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicity Role of Mitochondria in Alcoholic Liver Disease Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system.N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.Bimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals.Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes.Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice Peroxiredoxin III and sulfiredoxin together protect mice from pyrazole-induced oxidative liver injury.Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1 Role of CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic and non-alcoholic diseases.Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.myo-Inositol Oxygenase Overexpression Accentuates Generation of Reactive Oxygen Species and Exacerbates Cellular Injury following High Glucose Ambience: A NEW MECHANISM RELEVANT TO THE PATHOGENESIS OF DIABETIC NEPHROPATHY Human cytochrome P450 2E1 mutations that alter mitochondrial targeting efficiency and susceptibility to ethanol-induced toxicity in cellular models.Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease.Roles of alcohol and tobacco exposure in the development of hepatocellular carcinoma.Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.Mechanisms of drug toxicity and relevance to pharmaceutical development.Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.Novel insights into redox system and the mechanism of redox regulation.Emerging roles for brain drug-metabolizing cytochrome P450 enzymes in neuropsychiatric conditions and responses to drugs.Mitochondria-targeted heme oxygenase-1 induces oxidative stress and mitochondrial dysfunction in macrophages, kidney fibroblasts and in chronic alcohol hepatotoxicity Toxicity of food contaminant furan on liver and kidney of growing male rats.β-Naphthoflavone-Induced Mitochondrial Respiratory Damage in Cyp1 Knockout Mouse and in Cell Culture Systems: Attenuation by Resveratrol Treatment.1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice.Toxicological Implications of Mitochondrial Localization of CYP2E1.The effects of changes in glutathione levels through exogenous agents on intracellular cysteine content and protein adduct formation in chronic alcohol-treated VL17A cells.Preventive effects of indole-3-carbinol against alcohol-induced liver injury in mice via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms: Role of gut-liver-adipose tissue axis.Increased ethanol-inducible cytochrome P450-2E1 and cytochrome P450 isoforms in exosomes of alcohol-exposed rodents and patients with alcoholism through oxidative and endoplasmic reticulum stress.

P2860

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P2860

Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress.

http://www.wikidata.org/entity/Q34042602

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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type

label

Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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JBC.M110.121822

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Journal of Biological Chemistry

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Mitochondria-targeted cytochro ...... hol-mediated oxidative stress.

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Chuan-Peng Liu

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F Peter Guengerich

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Hindupur K Anandatheerthavarada

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Narayan G Avadhani

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Naresh B V Sepuri

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Seema Bansal

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Venkatesh Selvaraj

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P2860

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems

Mitochondrial targeted cytochrome P450 2E1 (P450 MT5) contains an intact N terminus and requires mitochondrial specific electron transfer proteins for activity

Targeting of NH2-terminal-processed microsomal protein to mitochondria: a novel pathway for the biogenesis of hepatic mitochondrial P450MT2

Physiological role of the N-terminal processed P4501A1 targeted to mitochondria in erythromycin metabolism and reversal of erythromycin-mediated inhibition of mitochondrial protein synthesis

Enzyme-specific transport of rat liver cytochrome P450 to the Golgi apparatus

Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes

Accumulation of mitochondrial P450MT2, NH(2)-terminal truncated cytochrome P4501A1 in rat brain during chronic treatment with beta-naphthoflavone. A role in the metabolism of neuroactive drugs

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24609-24619

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32

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285

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Ginger Lohr Milne

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