The Mre11 complex is required for ATM activation and the G2/M checkpoint
about
Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replicationHuman single-stranded DNA binding proteins are essential for maintaining genomic stabilityInfluence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and diseaseATM activation by ionizing radiation requires BRCA1-associated BAAT1ATM-dependent phosphorylation of ATF2 is required for the DNA damage responseDNA end resection by CtIP and exonuclease 1 prevents genomic instabilityInteraction between human MCM7 and Rad17 proteins is required for replication checkpoint signalingN terminus of CtIP is critical for homologous recombination-mediated double-strand break repairTargeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53Involvement of human MOF in ATM functionThe transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repairFunctional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppressionMdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retentionCommon mechanisms of PIKK regulationRapid activation of ATR by ionizing radiation requires ATM and Mre11Bacillus subtilis RecN binds and protects 3'-single-stranded DNA extensions in the presence of ATP.Mre11 assembles linear DNA fragments into DNA damage signaling complexesThe telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage responseActivation of the DNA Damage Response by RNA VirusesA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorChromatin perturbations during the DNA damage response in higher eukaryotesConcerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damageRecruitment and activation of the ATM kinase in the absence of DNA-damage sensors.A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responsesAberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing geneA role for the Tip60 histone acetyltransferase in the acetylation and activation of ATMMDC1 regulates DNA-PK autophosphorylation in response to DNA damageThe role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint controlThe HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damageHuman papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiationChk2 suppresses the oncogenic potential of DNA replication-associated DNA damageThe Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage ResponseAdenovirus type 5 early region 1B 55-kDa oncoprotein can promote cell transformation by a mechanism independent from blocking p53-activated transcriptionConserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damageNBN phosphorylation regulates the accumulation of MRN and ATM at sites of DNA double-strand breaksAdenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection.ATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication.Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum.DNA damage response during mouse oocyte maturation.
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P2860
The Mre11 complex is required for ATM activation and the G2/M checkpoint
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@ast
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@en
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@nl
type
label
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@ast
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@en
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@nl
prefLabel
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@ast
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@en
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@nl
P2093
P2860
P356
P1433
P1476
The Mre11 complex is required for ATM activation and the G2/M checkpoint
@en
P2093
Caroline E Lilley
Christian T Carson
Darwin V Lee
Matthew D Weitzman
Rachel A Schwartz
P2860
P304
P356
10.1093/EMBOJ/CDG630
P407
P577
2003-12-01T00:00:00Z