Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans
about
Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell developmentSecondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses.A gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene.Receptor selection in B and T lymphocytes.Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: sequence comparison reveals a putative recombinational enhancer element.Sequences affecting the V(D)J recombinational activity of the IgH intronic enhancer in a transgenic substrate.Molecular cloning of a zinc finger protein which binds to the heptamer of the signal sequence for V(D)J recombination.Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus.Kappa chain monoallelic demethylation and the establishment of allelic exclusion.Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers.Regulation of T cell receptor delta gene rearrangement by c-Myb.The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression.Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangementExpression of a targeted lambda 1 light chain gene is developmentally regulated and independent of Ig kappa rearrangements.Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibilityReceptor editing occurs frequently during normal B cell development.An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune systemThe V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrateA developmentally modulated chromatin structure at the mouse immunoglobulin kappa 3' enhancer.Enhancer control of local accessibility to V(D)J recombinase.Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.A developmentally controlled competitive STAT5-PU.1 DNA binding mechanism regulates activity of the Ig κ E3' enhancer.Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing.Regulation of V(D)J recombination by transcriptional promoters.Evidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment.Mechanism of e47-Pip interaction on DNA resulting in transcriptional synergy and activation of immunoglobulin germ line sterile transcripts.Coordinate transcription and V(D)J recombination of the kappa immunoglobulin light-chain locus: NF-kappaB-dependent and -independent pathways of activation.MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress.Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci.Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production.Regulation of T cell receptor delta gene rearrangement by CBF/PEBP2.
P2860
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P2860
Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@ast
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@en
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@nl
type
label
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@ast
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@en
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@nl
prefLabel
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@ast
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@en
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@nl
P2093
P2860
P1433
P1476
Deletion of the immunoglobulin ...... in gene rearrangement in trans
@en
P2093
P2860
P304
P407
P577
1993-06-01T00:00:00Z