Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1 - Wikidata - awgldk - TriplyDB

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

http://www.wikidata.org/entity/Q34116116

about

Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas Shepherding AKT and androgen receptor by Ack1 tyrosine kinase Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation Androgen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinases Targeting Cdc42 in cancer Ack1: Activation and Regulation by Allostery Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy.CrkI and p130(Cas) complex regulates the migration and invasion of prostate cancer cells Ack1 tyrosine kinase activation correlates with pancreatic cancer progression Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer ACK1 tyrosine kinase: targeted inhibition to block cancer cell proliferation Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation Drosophila activated Cdc42 kinase has an anti-apoptotic function Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli.miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases Bayesian Weibull tree models for survival analysis of clinico-genomic data A chemical and phosphoproteomic characterization of dasatinib action in lung cancer High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors.Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization.ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1 Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1 Two Distinct Categories of Focal Deletions in Cancer Genomes.Regulation of ack-family nonreceptor tyrosine kinases.ACK1/TNK2 tyrosine kinase: molecular signaling and evolving role in cancers.Mutation of androgen receptor N-terminal phosphorylation site Tyr-267 leads to inhibition of nuclear translocation and DNA binding Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways.Ack1 overexpression promotes metastasis and indicates poor prognosis of hepatocellular carcinoma.TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes.Discovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo.

P2860

Q21142629-E2BD6919-0966-4249-8F9C-06B8F57C62B8 Q24296458-01D89AB1-F7BF-49EA-AE6F-E5B487221889 Q24306771-F5D20230-EA20-4DFE-8174-43DF444533BA Q24308859-0B6D489A-728A-4513-A4F2-04AA48E47440 Q24317755-C3C43F95-A3AE-4DD0-BC91-D63C82483D93 Q24337716-32C3CAC5-006D-403D-B12B-6541505922C6 Q26866135-3779B17F-6A98-45D2-90E6-75A4D163C4A6 Q27028075-DF544D50-B7CF-4AD3-BF60-4281F483EDFA Q27675970-261066EB-0B82-4095-9901-033FA730AA9E Q27690752-5339A465-1402-46B0-A27D-381E26BF8939 Q28115754-B4D04DCF-BB66-4424-AAA3-759B43AD1906 Q28254665-AF82ACB8-51EF-4D3A-8294-D5F1A2EC8359 Q28259414-D7E5DB3C-FDDA-4EFC-B84B-34CB07B5B4D3 Q28266168-D235E5C4-3150-42CD-AC60-DAB5799E56DB Q28289188-931533D7-2652-4E6D-9478-9D0F90B1A895 Q28301664-F2B4D317-745D-400F-A91D-D35C49933889 Q28483782-FF64445D-CC17-4472-9AB3-30908538C5AD Q30010017-2CB822CA-BF54-4619-964B-A2C1DBF8174D Q30155858-CB2637A6-091C-4C9A-A78C-47A7B123A805 Q30156976-EF556BCD-89D5-4766-9800-BE3997DCFB9A Q30159764-9E91F199-434A-4814-B256-D53D6174101D Q30428483-F058FDF5-DDA5-4DB8-A633-0F914A7754F0 Q30433918-F10BCE5C-E6AB-450A-942B-9FEC08483F71 Q31162240-E8F58271-5E14-4814-8AC0-495FF7CDFFE4 Q33742159-E3D652E1-EF24-4D9F-A5D3-E7908C39DC6F Q33975831-6AD0F2F2-E73E-4038-A977-8F8A5DC8992F Q34301120-AA6633D9-16AC-4E90-B9F5-AD63610B6198 Q34317299-2AEC2073-30BE-4177-9DCF-F11B8F2A2B49 Q34650735-043406F9-2FAF-4C21-BDE0-71D4613E46F6 Q34785286-1F662417-384A-414E-9EB8-F223A1618FEF Q35006333-93A1F50F-727C-4BF7-A467-4ACE9AD8E1B4 Q35542942-67D9D83A-3C7D-4EC6-871E-F159774B774F Q35624046-80994D79-3614-4F08-A3F6-1907FA64B794 Q36437173-4368B159-34CD-4C45-A6FD-4D9063191FDA Q36557240-11D0BC08-B5A4-4A27-9EDF-648C29C6E382 Q36562108-45E9EB48-EBC7-46EA-BCB8-C616161B8552 Q36678720-EF96518B-B409-42C3-AB2D-70E0032F3896 Q36883168-905C54F0-D47B-46BE-A808-48F13419D041 Q37073073-AAD0411B-407D-4C3E-A111-8FC189068FA8 Q37133949-6EDBB5C8-C51A-456C-A710-570DFDBE3929

P2860

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

http://www.wikidata.org/entity/Q34116116

description

2005 nî lūn-bûn

@nan

2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@ast

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@en

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@nl

type

label

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@ast

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@en

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@nl

prefLabel

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@ast

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@en

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@nl

P1433

Q34116116-01B6D222-4423-49E5-9F8E-7DA651B6B207

P1476

Q34116116-A83292D4-DC29-46EE-864C-7E4E3FA1A605

P2093

Q34116116-0CCF94A4-8D67-491F-88A2-84399039CB51

Q34116116-24952156-01D1-4964-81CB-0563E6EA57C5

Q34116116-2CE61832-3A25-49B0-9751-E112F61A47BC

Q34116116-3A6403C3-65C3-41AF-91C3-808233609C27

Q34116116-8A451499-6B61-4551-85F8-1F0DB497931D

Q34116116-A2B24A10-6520-4013-90A5-5253A09BA3E7

Q34116116-A938621B-3C23-4462-B472-1BA15765D9BB

Q34116116-AAEA0F74-696F-4E13-BAD3-345F7675BC44

Q34116116-AFAD8656-5473-4D0E-AD18-873F5C1BFCE3

Q34116116-CCF5B955-9B54-42B0-AA31-AE5E4DB183CE

P2860

Q34116116-0F6EF218-7FC9-4C49-86FE-B4BEDAE2EF68

Q34116116-11AE72EB-77C3-4482-92DC-4C81AB3618B5

Q34116116-15FBAEBC-162D-41D2-98DF-AD9EFE85BAD5

Q34116116-2E21D9D7-912D-49CA-965E-F110C10A102C

Q34116116-3408B656-17D6-4E14-A06F-67A9DD63A26D

Q34116116-37E973EF-E2BF-47A2-BCEB-30D30AAE6D0F

Q34116116-3E9CEFB0-A46F-42F6-ADEB-8DB32ED4A40F

Q34116116-453651FB-EDA3-4EDD-9BA2-DDD13C6A97E2

Q34116116-46467DBD-CCB1-490E-ADD9-FAD6AF9ACEE1

Q34116116-4A348079-A945-4C66-AD5C-F6BF50DBD39A

P304

Q34116116-7E32026F-62F1-4232-8209-6344E6176248

P31

Q34116116-2B90337A-E2EF-47AB-9C53-39FA8B4BAD0B

P356

Q34116116-E708113C-4540-4B5B-B028-06FF6FAB009B

P407

Q34116116-B8724657-24BE-4850-9B7B-FD6D907E5173

P433

Q34116116-9D145083-F38A-4338-AEBD-B47D8C69B29B

P478

Q34116116-090142C4-B3A5-4DD0-89EC-A0A8569B0D55

P577

Q34116116-F8E1EDAD-7153-4E68-8D76-D6E2CEC0BB07

P5875

Q34116116-3F238483-A382-43E9-BBE3-5041E97FF246

P698

Q34116116-38A28D5E-79EB-4184-9E23-8854F6FD47FA

P932

Q34116116-4046682E-32BD-410C-B89F-255428452EF8

P356

PNAS.0508014102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

@en

P2093

Anthony Slavin

http://www.w3.org/2001/XMLSchema#string

Astrid Strelow

http://www.w3.org/2001/XMLSchema#string

Edward Htun van der Horst

http://www.w3.org/2001/XMLSchema#string

Holger Wesche

http://www.w3.org/2001/XMLSchema#string

Jessica Orf

http://www.w3.org/2001/XMLSchema#string

Ken Q C Nguyen

http://www.w3.org/2001/XMLSchema#string

Lawrence Chinn

http://www.w3.org/2001/XMLSchema#string

Lei-Hoon See

http://www.w3.org/2001/XMLSchema#string

Minqing Rong

http://www.w3.org/2001/XMLSchema#string

Scott Powers

http://www.w3.org/2001/XMLSchema#string

P2860

Expression profiling predicts outcome in breast cancer

Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

Epithelial-mesenchymal transitions in tumour progression

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation

Epidermal growth factor stimulation of the ACK1/Dbl pathway in a Cdc42 and Grb2-dependent manner

The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors

Genome-wide analysis of DNA copy-number changes using cDNA microarrays

P304

15901-15906

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0508014102

http://www.w3.org/2001/XMLSchema#string

P407

P433

44

http://www.w3.org/2001/XMLSchema#string

P478

102

http://www.w3.org/2001/XMLSchema#string

P577

2005-10-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7519713

http://www.w3.org/2001/XMLSchema#string

P698

16247015

http://www.w3.org/2001/XMLSchema#string

P932

1276100

http://www.w3.org/2001/XMLSchema#string