Extrapore residues of the S5-S6 loop of domain 2 of the voltage-gated skeletal muscle sodium channel (rSkM1) contribute to the mu-conotoxin GIIIA binding site.
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Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neuronsEnergetic localization of saxitoxin in its channel binding site.Molecular dynamics study of binding of µ-conotoxin GIIIA to the voltage-gated sodium channel Na(v)1.4.A proton leak current through the cardiac sodium channel is linked to mixed arrhythmia and the dilated cardiomyopathy phenotype.Arthropod venoms: a vast arsenal of insecticidal neuropeptides.Systematic study of binding of μ-conotoxins to the sodium channel NaV1.4.μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerveΑ- and β-subunit composition of voltage-gated sodium channels investigated with μ-conotoxins and the recently discovered μO§-conotoxin GVIIJ.Selective purification of recombinant neuroactive peptides using the flagellar type III secretion system.Speeding the recovery from ultraslow inactivation of voltage-gated Na+ channels by metal ion binding to the selectivity filter: a foot-on-the-door?mu-conotoxin GIIIA interactions with the voltage-gated Na(+) channel predict a clockwise arrangement of the domains.Electrostatic and steric contributions to block of the skeletal muscle sodium channel by mu-conotoxin.Trans-channel interactions in batrachotoxin-modified rat skeletal muscle sodium channels: kinetic analysis of mutual inhibition between mu-conotoxin GIIIA derivatives and amine blockersThe first gene-encoded amphibian neurotoxin.A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ.Subtype-selective targeting of voltage-gated sodium channels.Advances in targeting voltage-gated sodium channels with small molecules.Biophysics, pathophysiology, and pharmacology of ion channel gating pores.Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands.Residue Gly1326 of the N-type calcium channel alpha 1B subunit controls reversibility of omega-conotoxin GVIA and MVIIA block.Clockwise domain arrangement of the sodium channel revealed by (mu)-conotoxin (GIIIA) docking orientation.Mechanism and molecular basis for the sodium channel subtype specificity of µ-conopeptide CnIIICConotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel.The selectivity filter of the voltage-gated sodium channel is involved in channel activation.Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore.Molecular basis of isoform-specific micro-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels.Marine Toxins That Target Voltage-gated Sodium Channels.Importance of position 8 in μ-conotoxin KIIIA for voltage-gated sodium channel selectivity.
P2860
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P2860
Extrapore residues of the S5-S6 loop of domain 2 of the voltage-gated skeletal muscle sodium channel (rSkM1) contribute to the mu-conotoxin GIIIA binding site.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Extrapore residues of the S5-S ...... -conotoxin GIIIA binding site.
@ast
Extrapore residues of the S5-S ...... -conotoxin GIIIA binding site.
@en
Extrapore residues of the S5-S ...... skeletal muscle sodium channel
@nl
type
label
Extrapore residues of the S5-S ...... -conotoxin GIIIA binding site.
@ast
Extrapore residues of the S5-S ...... -conotoxin GIIIA binding site.
@en
Extrapore residues of the S5-S ...... skeletal muscle sodium channel
@nl
prefLabel
Extrapore residues of the S5-S ...... -conotoxin GIIIA binding site.
@ast
Extrapore residues of the S5-S ...... -conotoxin GIIIA binding site.
@en
Extrapore residues of the S5-S ...... skeletal muscle sodium channel
@nl
P2093
P2860
P1433
P1476
Extrapore residues of the S5-S ...... -conotoxin GIIIA binding site.
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(98)77510-1
P407
P577
1998-07-01T00:00:00Z