Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.
about
Hematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsTransplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.Long-term expression of a T-cell receptor beta-chain gene in mice reconstituted with retrovirus-infected hematopoietic stem cells.Inhibition of hematopoietic development from embryonic stem cells by antisense vav RNA.Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells.Adenosine deaminase deficiency as the first target disorder in gene therapy.Bone marrow extracellular matrix molecules improve gene transfer into human hematopoietic cells via retroviral vectors.Gene therapy: here to stay.Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cellsGene therapy for canine leukocyte adhesion deficiency with lentiviral vectors using the murine stem cell virus and human phosphoglycerate kinase promoters.Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo.A murine model for B-lymphocyte somatic cell gene therapy.Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes.Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivoHuman cord blood cells as targets for gene transfer: potential use in genetic therapies of severe combined immunodeficiency disease.High efficiency retroviral mediated gene transduction into single isolated immature and replatable CD34(3+) hematopoietic stem/progenitor cells from human umbilical cord blood.Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infectionExpression of the gibbon ape leukemia virus receptor-1 in rhesus macaque tissues.Retroviral-mediated transfer of the human acid sphingomyelinase cDNA: correction of the metabolic defect in cultured Niemann-Pick disease cellsLong-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.Development of gene therapy: potential in severe combined immunodeficiency due to adenosine deaminase deficiency.The level of mRNA encoding the amphotropic retrovirus receptor in mouse and human hematopoietic stem cells is low and correlates with the efficiency of retrovirus transduction.Gene therapy: current status and future directions.Transduction of CD34+ hematopoietic progenitor cells with an antitat gene protects T-cell and macrophage progeny from AIDS virus infection.A new retrovirus packaging cell for gene transfer constructed from amplified long terminal repeat-free chimeric proviral genes.Expression of human adenosine deaminase in mice transplanted with hemopoietic stem cells infected with amphotropic retroviruses.Development of a high-titer retrovirus producer cell line and strategies for retrovirus-mediated gene transfer into rhesus monkey hematopoietic stem cells.Cell cycle dependence of retroviral transduction: An issue of overlapping time scales.A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors.
P2860
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P2860
Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.
description
1989 nî lūn-bûn
@nan
1989 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Long-term expression of human ...... cted hematopoietic stem cells.
@ast
Long-term expression of human ...... cted hematopoietic stem cells.
@en
Long-term expression of human ...... cted hematopoietic stem cells.
@nl
type
label
Long-term expression of human ...... cted hematopoietic stem cells.
@ast
Long-term expression of human ...... cted hematopoietic stem cells.
@en
Long-term expression of human ...... cted hematopoietic stem cells.
@nl
prefLabel
Long-term expression of human ...... cted hematopoietic stem cells.
@ast
Long-term expression of human ...... cted hematopoietic stem cells.
@en
Long-term expression of human ...... cted hematopoietic stem cells.
@nl
P2093
P2860
P356
P1476
Long-term expression of human ...... cted hematopoietic stem cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.22.8892
P407
P577
1989-11-01T00:00:00Z