Expression of the human beta-globin gene following retroviral-mediated transfer into multipotential hematopoietic progenitors of mice.
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Intron requirement for expression of the human purine nucleoside phosphorylase geneCurrent and future alternative therapies for beta-thalassemia majorHematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsDevelopment of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses.Gene therapy for the hemoglobin disorders: past, present, and future.Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.The beta-globin locus control region versus gene therapy vectors: a struggle for expression.Correction of glucocerebrosidase deficiency after retroviral-mediated gene transfer into hematopoietic progenitor cells from patients with Gaucher disease.Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cellsProduction of human glucocerebrosidase in mice after retroviral gene transfer into multipotential hematopoietic progenitor cells.Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow.Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia.Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells.A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation.Adeno-associated virus type 2-mediated transduction of murine hematopoietic cells with long-term repopulating ability and sustained expression of a human globin gene in vivo.Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease.Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene.Mock retroviral infection alters the developmental potential of murine bone marrow stem cells.A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.Gene therapy for hemoglobinopathies: progress and challenges.Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structureGene therapy in thalassemia and hemoglobinopathies.Gene therapy: current status and future directions.Recent advances in gene therapy for thalassemia.Slow and Steady Wins The Race? Progress in the Development of Vectors for Gene Therapy of β-Thalassemia and Sickle Cell Disease.Emerging cellular and gene therapies for congenital anemias.The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.A new retrovirus packaging cell for gene transfer constructed from amplified long terminal repeat-free chimeric proviral genes.Development of a high-titer retrovirus producer cell line and strategies for retrovirus-mediated gene transfer into rhesus monkey hematopoietic stem cells.Ex vivo expansion and selection of retrovirally transduced bone marrow: an efficient methodology for gene-transfer to murine lympho-haemopoietic stem cells.Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia.
P2860
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P2860
Expression of the human beta-globin gene following retroviral-mediated transfer into multipotential hematopoietic progenitors of mice.
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Expression of the human beta-g ...... topoietic progenitors of mice.
@ast
Expression of the human beta-g ...... topoietic progenitors of mice.
@en
type
label
Expression of the human beta-g ...... topoietic progenitors of mice.
@ast
Expression of the human beta-g ...... topoietic progenitors of mice.
@en
prefLabel
Expression of the human beta-g ...... topoietic progenitors of mice.
@ast
Expression of the human beta-g ...... topoietic progenitors of mice.
@en
P2093
P2860
P356
P1476
Expression of the human beta-g ...... topoietic progenitors of mice.
@en
P2093
Karlsson S
Nienhuis AW
Papayannopoulou T
P2860
P304
P356
10.1073/PNAS.85.16.6062
P407
P577
1988-08-01T00:00:00Z