Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system.
about
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repairDirect regulation of CREB transcriptional activity by ATM in response to genotoxic stressMitochondrial dysfunction in ataxia-telangiectasiaCytoplasmic ATM in neurons modulates synaptic functionEssential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesMolecular pathology of ataxia telangiectasiaCurrent Evidence for Developmental, Structural, and Functional Brain Defects following Prenatal Radiation ExposureAtaxia telangiectasia: a reviewNuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cellsRegulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cellsAtaxia telangiectasia mutated is essential during adult neurogenesisAtm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous systemDefective neurogenesis resulting from DNA ligase IV deficiency requires AtmRad50 is dispensable for the maintenance and viability of postmitotic tissuesChk2 suppresses the oncogenic potential of DNA replication-associated DNA damageGenetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and developmentOxidative stress-induced DNA damage and cell cycle regulation in B65 dopaminergic cell lineCaspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspasesRapid phosphorylation of histone H2A.X following ionotropic glutamate receptor activationPhosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal deathBRCA2 is required for neurogenesis and suppression of medulloblastomaAccumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient miceIn vivo importance of homologous recombination DNA repair for mouse neural stem and progenitor cellsEarly postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genesA novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden.Neuronal death is an active, caspase-dependent process after moderate but not severe DNA damage.The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilizationInteraction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition.Convergent transcription through a long CAG tract destabilizes repeats and induces apoptosisATM is down-regulated by N-Myc-regulated microRNA-421.Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene.The p53 pathway and apoptosis.Breast cancer: genetic predisposition and exposure to radiation.A novel role for ATM in regulating proteasome-mediated protein degradation through suppression of the ISG15 conjugation pathway.Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromesDR5 knockout mice are compromised in radiation-induced apoptosisDNA repair on the brain.Maintaining genome stability in the nervous system.Atm is dispensable for p53 apoptosis and tumor suppression triggered by cell cycle dysfunction.Control of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18(Ink4c) and p19(Ink4d)
P2860
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P2860
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Requirement for Atm in ionizin ...... loping central nervous system.
@ast
Requirement for Atm in ionizin ...... loping central nervous system.
@en
Requirement for Atm in ionizin ...... loping central nervous system.
@nl
type
label
Requirement for Atm in ionizin ...... loping central nervous system.
@ast
Requirement for Atm in ionizin ...... loping central nervous system.
@en
Requirement for Atm in ionizin ...... loping central nervous system.
@nl
prefLabel
Requirement for Atm in ionizin ...... loping central nervous system.
@ast
Requirement for Atm in ionizin ...... loping central nervous system.
@en
Requirement for Atm in ionizin ...... loping central nervous system.
@nl
P2093
P1433
P1476
Requirement for Atm in ionizin ...... loping central nervous system.
@en
P2093
P304
P356
10.1126/SCIENCE.280.5366.1089
P407
P577
1998-05-01T00:00:00Z