Cell cycle- and chromatin binding state-dependent phosphorylation of human MCM heterohexameric complexes. A role for cdc2 kinase.
about
The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phaseChk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restartCdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin bindingHuman cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication.Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinasesGenomic instability in cancer.Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells.Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2Biochemical activities associated with mouse Mcm2 proteinCell cycle-dependent proteolysis and phosphorylation of human Mcm10Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factorsExpression profiling of gastric adenocarcinoma using cDNA array.Architecture of replication compartments formed during Epstein-Barr virus lytic replication.Functional cooperation between FACT and MCM is coordinated with cell cycle and differential complex formation.Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.Phosphorylation of Mcm4 at specific sites by cyclin-dependent kinase leads to loss of Mcm4,6,7 helicase activity.Identification of MCM4 as a target of the DNA replication block checkpoint system.Cdc7 kinase complex: a key regulator in the initiation of DNA replication.Replication licensing and the DNA damage checkpoint.Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin.Different phenotypes in vivo are associated with ATPase motif mutations in Schizosaccharomyces pombe minichromosome maintenance proteinsPhosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication.Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.Chromatin remodeler sucrose nonfermenting 2 homolog (SNF2H) is recruited onto DNA replication origins through interaction with Cdc10 protein-dependent transcript 1 (Cdt1) and promotes pre-replication complex formation.Eukaryotic MCM proteins: beyond replication initiation.Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1Human papillomavirus E7 induces rereplication in response to DNA damageCharacterization of conserved arginine residues on Cdt1 that affect licensing activity and interaction with Geminin or Mcm complex.Cyclin A-Cdk1 regulates the origin firing program in mammalian cells.Isolation and characterization of various complexes of the minichromosome maintenance proteins of Schizosaccharomyces pombe.A spontaneous Cdt1 mutation in 129 mouse strains reveals a regulatory domain restraining replication licensing.A novel intermediate in initiation complex assembly for fission yeast DNA replication.Distinct phosphoisoforms of the Xenopus Mcm4 protein regulate the function of the Mcm complexCyclin A promotes S-phase entry via interaction with the replication licensing factor Mcm7.Persistent p21 expression after Nutlin-3a removal is associated with senescence-like arrest in 4N cells.Transient nutlin-3a treatment promotes endoreduplication and the generation of therapy-resistant tetraploid cellsHepatitis B virus X protein increases the Cdt1-to-geminin ratio inducing DNA re-replication and polyploidy.Site-specific phosphorylation of MCM4 during the cell cycle in mammalian cells.Human cytomegalovirus prevents replication licensing by inhibiting MCM loading onto chromatin.
P2860
Q24290559-177C170F-D14E-49CD-8380-7075F565ACBEQ24301492-8CCB73A3-3E8B-4FDC-AD87-6A1E8107DBC4Q24313280-9C944778-B1C1-421C-8518-E5898F32B574Q24541379-226920D6-3874-4F26-858C-6021BF8F654BQ24553131-E57DA669-C465-4359-939B-704576273101Q24564474-124DD51F-4581-4F28-A312-E0B929C3C3E0Q27013707-7077C20C-8C5F-430A-81FB-4533BFC31E47Q27313730-B704048D-E8E1-4FA4-AD4A-9F17DA3E4799Q28140699-0EB57782-E7E1-4DDD-ACFB-AF663061DAC6Q28188528-8FF3E39E-B22B-4A05-B2C6-C16F9FCD265BQ28198815-FF5998EE-DE83-4151-9907-187D15071F6FQ28587270-22926814-D9FC-4246-A2F0-1F96A9BC318BQ30307391-A7FA63C5-98AC-4C0A-8866-10378D8BEB10Q33737678-06E3D0EE-9599-49C5-8242-CAD8D248E5DAQ33763423-5590A0F0-8C1B-4BB9-8E8D-6AAEF9652AF2Q33872351-C9B2FDC5-F340-48AE-869D-3FB72D12A903Q34084017-F2AFB198-E021-49AA-AC3D-03C97ED3F247Q34192831-31F7DB75-A01A-4894-B444-0AB80884A354Q34539989-7C0E6B83-F93D-419D-90F6-479842DB8566Q34547673-A9DDC084-B452-41F0-80BF-04CBA8EDC633Q34574600-64B40EBE-146A-44FE-B48E-D08366345470Q34614810-435A5DAD-78E1-4952-BA32-DC2CF55B465FQ35101480-EF6C37D1-A1B6-4FBB-9DF5-5144DAD45F3FQ35107397-37AD67C5-3307-4D8D-876E-60A84E516F76Q35604309-ED47DC53-D77B-4824-B91C-F4BCF5F1941AQ35684975-66F77DBF-EA20-48E8-A7CB-F1048D192158Q36489137-AB70BE14-0B51-441F-A2C4-B5B3CE8F74DAQ36559551-37D4A6EE-1616-4BD0-BA4E-1C8A14822EE4Q36956930-12C4BD1C-4FB7-46B2-B002-021D91530712Q37117765-F6A80797-31B3-4581-8885-6D80CA0BFFF5Q38313205-68941AAE-FB6C-40DB-9B0C-84F0B788C499Q39132054-977389C5-0F56-47F1-A3D1-B0F7B7C4F967Q39284579-064DE911-7A12-4C77-B19F-FA72BEDA5A88Q39452917-EA8E2BE3-7A11-4F91-B751-3A430A7EFC4CQ39631585-1A44AA30-B0EE-46E0-B61E-56C726782CEAQ39701774-A685CA65-B07B-4580-9F59-F631EA658942Q39929026-58BDC91E-69FE-4300-9905-65006AA2752CQ39951895-D11ADE9E-BF11-4F00-993D-A19287A5B9BBQ40308248-B3B4CDAA-A23B-44F5-854F-0721BE30F8B0Q40663239-1500C09D-9ED6-4A48-88A7-D251BD6D22E9
P2860
Cell cycle- and chromatin binding state-dependent phosphorylation of human MCM heterohexameric complexes. A role for cdc2 kinase.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@ast
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@en
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@nl
type
label
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@ast
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@en
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@nl
prefLabel
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@ast
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@en
Cell cycle- and chromatin bind ...... lexes. A role for cdc2 kinase.
@nl
P2093
P2860
P356
P1476
Cell cycle- and chromatin bind ...... plexes. A role for cdc2 kinase
@en
P2093
P2860
P304
17095-17101
P356
10.1074/JBC.273.27.17095
P407
P577
1998-07-01T00:00:00Z