Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.
about
Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4Importin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domainRoles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistanceDifferential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanismsMolecular Targeting of ERKs/RSK2 Signaling Axis in Cancer PreventionRegulation of Raf through phosphorylation and N terminus-C terminus interactionRegulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoformsB-Raf and Raf-1 are regulated by distinct autoregulatory mechanismsSGK1: The Dark Side of PI3K Signaling.Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: potential involvement of the PI3K pathway in FSH signaling.Serum/glucocorticoid-inducible kinase can phosphorylate the cyclic AMP response element binding protein, CREB.BRAF activation initiates but does not maintain invasive prostate adenocarcinomaDown-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation.Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells.Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1Negative regulation of SEK1 signaling by serum- and glucocorticoid-inducible protein kinase 1.Targeting the mitogen-activated protein kinase cascade to treat cancer.Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins.Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation.Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.Epithelial sodium channel regulated by differential composition of a signaling complexSerum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell deathA computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics.Role of Ras/Raf/MEK/ERK signaling in physiological hematopoiesis and leukemia development.FoxO transcription factors: their roles in the maintenance of skeletal muscle homeostasis.Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation.Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.The N-terminus of the serum- and glucocorticoid-inducible kinase Sgk1 specifies mitochondrial localization and rapid turnover.Hepatic serum- and glucocorticoid-regulated protein kinase 1 (SGK1) regulates insulin sensitivity in mice via extracellular-signal-regulated kinase 1/2 (ERK1/2).Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions.Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway.Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.Hypotonic activation of volume-sensitive outwardly rectifying chloride channels in cultured PASMCs is modulated by SGK.Therapeutic inhibition of SGK1 suppresses colorectal cancer.
P2860
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P2860
Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@ast
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@en
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@nl
type
label
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@ast
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@en
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@nl
prefLabel
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@ast
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@en
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@nl
P2093
P2860
P356
P1476
Serum- and glucocorticoid-indu ...... nd negatively regulates B-Raf.
@en
P2093
P2860
P304
31620-31626
P356
10.1074/JBC.M102808200
P407
P577
2001-06-15T00:00:00Z