Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.
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Role of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiologyRole of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cellsMetabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathwayA fluorescence-based high-throughput assay for the discovery of exchange protein directly activated by cyclic AMP (EPAC) antagonistsUrocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery: Role of EPAC2 and ERK1/2Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeuticsRecent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).Cyclic AMP accelerates calcium waves in pancreatic acinar cellscAMP analogs and their metabolites enhance TREK-1 mRNA and K+ current expression in adrenocortical cells.PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemiaACTH induces Cav3.2 current and mRNA by cAMP-dependent and cAMP-independent mechanisms.beta-Adrenergic activation of electrogenic K+ and Cl- secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways.β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent.Activation of exchange protein activated by cAMP in the rat basolateral amygdala impairs reconsolidation of a memory associated with self-administered cocaine.5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP.Cyclic AMP sensor EPAC proteins and energy homeostasis.Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1.A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer.Identification and characterization of small molecules as potent and specific EPAC2 antagonists.Prostaglandin dehydrogenase (PGDH) in granulosa cells of primate periovulatory follicles is regulated by the ovulatory gonadotropin surge via multiple G proteins.Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca2+ in female mouse islets stimulated by glucose and tolbutamide.An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.Opposing roles of PKA and EPAC in the cAMP-dependent regulation of schwann cell proliferation and differentiation [corrected]Prostaglandin E2 reduces the release and infectivity of new cell-free virions and cell-to-cell HIV-1 transfer.Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes.TORC: a new twist on corticotropin-releasing hormone gene expression8-Phenylthio-adenines stimulate the expression of steroid hydroxylases, Cav3.2 Ca²⁺ channels, and cortisol synthesis by a cAMP-independent mechanism.cAMP-guanine exchange factor protection from bile acid-induced hepatocyte apoptosis involves glycogen synthase kinase regulation of c-Jun NH2-terminal kinaseRp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion.cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of EpacReactive oxygen species (ROS) play a critical role in the cAMP-induced activation of Ras and the phosphorylation of ERK1/2 in Leydig cellscAMP and Epac in the regulation of tissue fibrosis.Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity.Epac activation sensitizes rat sensory neurons through activation of Ras.Under construction: building the macromolecular superstructure and signaling components of an electrical synapse.The Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules.Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.Efficient Synthesis of ESI-09, A Novel Non-cyclic Nucleotide EPAC AntagonistACTH inhibits bTREK-1 K+ channels through multiple cAMP-dependent signaling pathways
P2860
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P2860
Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@ast
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@en
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@nl
type
label
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@ast
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@en
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@nl
prefLabel
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@ast
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@en
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@nl
P2093
P2860
P1433
P1476
Epac-selective cAMP analogs: n ...... e nucleotide exchange factors.
@en
P2093
Frank Schwede
George G Holz
Oleg G Chepurny
P2860
P356
10.1016/J.CELLSIG.2007.07.009
P577
2007-07-25T00:00:00Z