Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
about
beta-Amyloid degradation and Alzheimer's diseaseAcyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptideNeural stem/progenitor cells in Alzheimer's diseaseAlzheimer's Disease: Mechanism and Approach to Cell TherapyATP effects on insulin-degrading enzyme are mediated primarily through its triphosphate moietyMutation of active site residues of insulin-degrading enzyme alters allosteric interactionsEpidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss.Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.Systemic catabolism of Alzheimer's Abeta40 and Abeta42.Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease.Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase.Effects of 4-hydroxy-nonenal and Amyloid-beta on expression and activity of endothelin converting enzyme and insulin degrading enzyme in SH-SY5Y cells.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesisHypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons.Gene-environment interaction research and transgenic mouse models of Alzheimer's disease.Ace revisited: a new target for structure-based drug design.Reduced fertility in male mice deficient in the zinc metallopeptidase NL1N-acetylcysteine prevents 4-hydroxynonenal- and amyloid-beta-induced modification and inactivation of neprilysin in SH-SY5Y cellsAmyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivoAmyloid, presenilins, and Alzheimer's disease.Identification and quantification of amyloid beta-related peptides in human plasma using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Antihypertensive drugs, prevention of cognitive decline and dementia: a systematic review of observational studies, randomized controlled trials and meta-analyses, with discussion of potential mechanisms.Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomyopathy.An antibody to the beta-secretase cleavage site on amyloid-beta-protein precursor inhibits amyloid-beta production.Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathyLipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling.Role of water-soluble amyloid-beta in the pathogenesis of Alzheimer's disease.Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysinCurrent concepts in therapeutic strategies targeting cognitive decline and disease modification in Alzheimer's disease.Identification and functional analysis of damage-induced neuronal endopeptidase (DINE), a nerve injury associated molecule.The involvement of lipid rafts in Alzheimer's disease.Advances in the pathogenesis of Alzheimer's disease: a re-evaluation of amyloid cascade hypothesis.Metal homeostasis in Alzheimer's disease.Current strategies for the treatment of Alzheimer's disease and other tauopathies.Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer's diseaseThe Role of the Renin-Angiotensin System in Amyloid Metabolism of Alzheimer's DiseaseThe effect of LCZ696 (sacubitril/valsartan) on amyloid-β concentrations in cerebrospinal fluid in healthy subjectsAging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology.ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease.
P2860
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P2860
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
@ast
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
@en
Beta-amyloid catabolism: roles for neprilysin
@nl
type
label
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
@ast
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
@en
Beta-amyloid catabolism: roles for neprilysin
@nl
prefLabel
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
@ast
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
@en
Beta-amyloid catabolism: roles for neprilysin
@nl
P1476
Beta-amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases?
@en
P2093
Anthony J Turner
Julie A Carson
P356
10.1046/J.1471-4159.2002.00855.X
P407
P577
2002-04-01T00:00:00Z