Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme.
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Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target ProteinDimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress ResponsesAPE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survivalMass spectrometry-based carboxyl footprinting of proteins: method evaluation.Disulfide bond formation contributes to herpes simplex virus capsid stability and retention of pentons.APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsRole of the DNA base excision repair protein, APE1 in cisplatin, oxaliplatin, or carboplatin induced sensory neuropathyIdentification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitorsSpecific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell linesApurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2.The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate.The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation.Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growthKnock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and functionCharacterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease.APE1, the DNA base excision repair protein, regulates the removal of platinum adducts in sensory neuronal cultures by NEREndothelial cell tumor growth is Ape/ref-1 dependentS-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodiesSmall-molecule inhibitors of DNA damage-repair pathways: an approach to overcome tumor resistance to alkylating anticancer drugs.Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral NeuropathyRef-1/APE1 as a Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia.NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1.Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer.APE1/Ref-1 knockdown in pancreatic ductal adenocarcinoma - characterizing gene expression changes and identifying novel pathways using single-cell RNA sequencing.The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel.APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells.Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival
P2860
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P2860
Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@ast
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@en
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@nl
type
label
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@ast
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@en
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@nl
prefLabel
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@ast
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@en
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@nl
P2093
P2860
P356
P1433
P1476
Interactions of apurinic/apyri ...... te conformation of the enzyme.
@en
P2093
Don L Rempel
Mark R Kelley
Meihua Luo
Michael L Gross
Sarah Delaplane
P2860
P356
10.1021/BI101248S
P407
P577
2010-12-08T00:00:00Z