Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
about
A Survey of Strategies to Modulate the Bone Morphogenetic Protein Signaling Pathway: Current and Future PerspectivesDIPG in Children - What Can We Learn from the Past?Pre-Clinical Models of Diffuse Intrinsic Pontine GliomaPathology, Molecular Genetics, and Epigenetics of Diffuse Intrinsic Pontine GliomaFuture Clinical Trials in DIPG: Bringing Epigenetics to the ClinicHistone modifications and a choice of variant: a language that helps the genome express itselfMolecular characteristics of pediatric high-grade gliomasEpigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumorsHistone H3 mutations--a special role for H3.3 in tumorigenesis?Chromatin signatures of cancerSpatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeuticsPre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma ModelsA high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agentInherited Disease Genetics Improves the Identification of Cancer-Associated GenesDiffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic TargetsA Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG).Pediatric high-grade glioma: biologically and clinically in need of new thinkingACVR1 mutations in DIPG: lessons learned from FOP.Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomasA sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas.Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.Targeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas.Management of high-grade gliomas in the pediatric patient: Past, present, and future.Histone H3.3 and cancer: A potential reader connection.Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.Detecting the H3F3A mutant allele found in high-grade pediatric glioma by real-time PCR.MethPed: a DNA methylation classifier tool for the identification of pediatric brain tumor subtypes.The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells.Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypesA Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells.Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.Mutations in chromatin machinery and pediatric high-grade gliomaMolecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor.Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma.Pediatric gliomas as neurodevelopmental disordersABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B-Driven Brainstem Glioma Model.Identification of complex genomic rearrangements in cancers using CouGaRCharacterizing and targeting PDGFRA alterations in pediatric high-grade glioma.
P2860
Q26739015-BEC220F7-89D8-4280-8059-CD9BE1D38F73Q26777843-06207F8F-F820-4A70-94BC-B4EDB4F00563Q26799976-94B3612E-1CFB-4395-890C-E97DE6E29424Q26801528-5429DBA4-CD84-4DF1-8399-1DD7D39B16C1Q26801858-C8EB8802-D0C1-4208-8894-2342B3192D2BQ26823316-E7574E18-48AB-42FF-A7DC-97BADEAF7F94Q26860786-F593A3AD-D47D-4C61-9272-679BBE5C230EQ26864920-230079B5-E4DA-4851-8012-83D5C36CA496Q26865965-FB0D2645-E34D-498D-8B65-2CE9056C2F2BQ27024162-D87979E0-7997-4C18-BA8A-453C3318EAE0Q27317083-E05E687D-3D9E-4BE2-9901-FEDD2293DEBCQ28468398-D256EB6A-A6D6-407B-BB13-633C683DCBE6Q28543923-579E1C67-07F3-4C33-9E6E-1FDFC65A34CEQ28550275-212AAA5B-5F8D-4E66-8358-548900ABF0DFQ30251385-1B7DF736-B5F4-4CCE-9258-16CB435B57E2Q33615351-51773F3A-34C0-4727-9ED0-6B75379E51B7Q33777868-5767C722-5BC8-4327-B86C-2E5FA0C165B4Q34134675-8848421F-0C04-4880-98AB-A4C50781F000Q34313807-847C3B74-477F-4800-8C23-FCAAD9D3B16FQ34363432-ADD6AE9E-D4F2-437D-854F-F753195B880EQ34363489-A546CCA6-3ED3-49A6-89D9-3739344CF13EQ34410560-2205F1DE-580C-4784-AF13-DF66C153E113Q34552042-1B3ED76C-AA96-44E1-B3C2-CEADDEB9DCABQ35206259-F5D402BE-052F-4BDE-9F84-01B982F79923Q35699403-6D60C720-4B00-44B7-9D80-81F061649824Q35754390-1CA79D40-ED29-4033-8045-F7CB0B62643EQ35777520-90CF5772-29FC-48E4-9C25-FF4B43758E59Q35831225-46668C69-338E-4639-BDE1-32E506306037Q36045385-63B475B0-6013-43B6-A96A-FF72B7C15EE5Q36303824-A96AA977-58BC-4702-ADDB-57BB1BA0E17CQ36527913-975BC9AF-7B65-45D2-B9A6-EC4C76AB4E55Q36561184-9763A18B-43D1-4E99-8E17-F26CC3EAE000Q36578816-87CE02E0-BB54-45AA-9D42-3C05247F45FCQ36716785-7F5024E7-B029-465A-8B21-18E670FD199DQ36738953-B5FEADA5-EB4F-4FB7-98FB-17B7FF70AB2FQ36774588-9E496D67-015D-4473-8A46-C5A583C3C683Q36803476-AB8D82EF-E43E-46F8-AF2F-26A5AAF11323Q36918220-E7E60463-EF2C-4B67-96B3-7254B1ADBD7EQ37548472-EF18607F-4EF2-4D61-A959-3AF5E931638DQ37662300-10D0D1D1-DFE4-461A-B8E9-3987E492D43C
P2860
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@ast
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@en
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@nl
type
label
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@ast
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@en
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@nl
prefLabel
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@ast
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@en
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@nl
P2093
P2860
P50
P356
P1433
P1476
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
@en
P2093
Adam M Fontebasso
Almos Klekner
Anne Bendel
Anne-Sophie Carret
Aoife Corcoran
Azra H Ligon
Benjamin Ellezam
Damien Faury
Daniel C Bowers
David T W Jones
P2860
P2888
P304
P356
10.1038/NG.2950
P407
P50
P577
2014-04-06T00:00:00Z
P5875
P6179
1028168538