Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
about
Comparative genomics and molecular dynamics of DNA repeats in eukaryotesZinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cellsMechanistic features of CAG*CTG repeat contractions in cultured cells revealed by a novel genetic assayInverted repeat-stimulated sister-chromatid exchange events are RAD1-independent but reduced in a msh2 mutant.Advances in mechanisms of genetic instability related to hereditary neurological diseases.Identification of RTG2 as a modifier gene for CTG*CAG repeat instability in Saccharomyces cerevisiaeLocalization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase IEmergence and evolution of Zfp36l3Huntington disease expansion mutations in humans can occur before meiosis is completed.Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiaeFriedreich's ataxia (GAA)n•(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae.Microsatellites: genomic distribution, putative functions and mutational mechanisms: a review.Mini- and microsatellite expansions: the recombination connection.Hsp90 modulates CAG repeat instability in human cells.Genetic instability induced by overexpression of DNA ligase I in budding yeast.Cis-elements governing trinucleotide repeat instability in Saccharomyces cerevisiae.Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells.CTG repeat instability and size variation timing in DNA repair-deficient mice.Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability.SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination.Repeat instability during DNA repair: Insights from model systemsWhere the crossovers are: recombination distributions in mammals.Repeat instability: mechanisms of dynamic mutations.Features of trinucleotide repeat instability in vivo.Molecular Markers for Biomass Traits: Association, Interaction and Genetic Divergence in Silkworm Bombyx moriModels for chromosomal replication-independent non-B DNA structure-induced genetic instability.Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stabilityStress-induced modulators of repeat instability and genome evolutionChromatin modifications and DNA repair: beyond double-strand breaks.DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro.Recombinational DNA repair is regulated by compartmentalization of DNA lesions at the nuclear pore complex.Role of recombination and replication fork restart in repeat instability.Long palindromic sequences induce double-strand breaks during meiosis in yeast.Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells.Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility.Both CAG repeats and inverted DNA repeats stimulate spontaneous unequal sister-chromatid exchange in Saccharomyces cerevisiae.Effects of sequence on repeat expansion during DNA replication.Recombination-induced CAG trinucleotide repeat expansions in yeast involve the MRE11-RAD50-XRS2 complex.The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats.Energetic coupling between clustered lesions modulated by intervening triplet repeat bulge loops: allosteric implications for DNA repair and triplet repeat expansion.
P2860
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P2860
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
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2000年论文
@wuu
name
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
@ast
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
@en
type
label
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
@ast
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
@en
prefLabel
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
@ast
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
@en
P2093
P2860
P356
P1476
Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast.
@en
P2093
P2860
P304
P356
10.1073/PNAS.040460297
P407
P577
2000-02-01T00:00:00Z