Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability
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Comparative genomics and molecular dynamics of DNA repeats in eukaryotesIn vivo and in vitro studies of Mgs1 suggest a link between genome instability and Okazaki fragment processing.Advances in mechanisms of genetic instability related to hereditary neurological diseases.Nucleases in homologous recombination as targets for cancer therapyContinuous and periodic expansion of CAG repeats in Huntington's disease R6/1 miceThe MPH1 gene of Saccharomyces cerevisiae functions in Okazaki fragment processing.Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiaeInteractions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeastIncision-dependent and error-free repair of (CAG)(n)/(CTG)(n) hairpins in human cell extractsMechanisms by which Bloom protein can disrupt recombination intermediates of Okazaki fragment maturation.Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiaeHMGB1: roles in base excision repair and related function.Requirement for flap endonuclease 1 (FEN1) to maintain genomic stability and transcriptional gene silencing in Arabidopsis.The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.Genetic instability induced by overexpression of DNA ligase I in budding yeast.An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiaePostreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.Repeat instability during DNA repair: Insights from model systemsBiochemical studies of the Saccharomyces cerevisiae Mph1 helicase on junction-containing DNA structuresAP endonuclease 1 prevents trinucleotide repeat expansion via a novel mechanism during base excision repair.Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner.DNA base excision repair: a mechanism of trinucleotide repeat expansion.Repeat instability: mechanisms of dynamic mutations.The role of DNA exonucleases in protecting genome stability and their impact on ageing.Mutations in DNA2 link progressive myopathy to mitochondrial DNA instability.A Whole Genome Screen for Minisatellite Stability Genes in Stationary-Phase Yeast CellsFlap endonuclease 1.Features of trinucleotide repeat instability in vivo.Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion.Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.Dna2 on the road to Okazaki fragment processing and genome stability in eukaryotes.A saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instabilityReplication stalling and DNA microsatellite instability.Myotonic dystrophy: disease repeat range, penetrance, age of onset, and relationship between repeat size and phenotypes.Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats.Chemotherapeutic deletion of CTG repeats in lymphoblast cells from DM1 patients.Expansion of CAG repeats in Escherichia coli is controlled by single-strand DNA exonucleases of both polarities.Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure.Physical and functional interactions between nucleosomes and Rad27, a critical component of DNA processing during DNA metabolism.Missed cleavage opportunities by FEN1 lead to Okazaki fragment maturation via the long-flap pathway.
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P2860
Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on May 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Saccharomyces cerevisiae flap ...... ntain triplet repeat stability
@en
Saccharomyces cerevisiae flap ...... tain triplet repeat stability.
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type
label
Saccharomyces cerevisiae flap ...... ntain triplet repeat stability
@en
Saccharomyces cerevisiae flap ...... tain triplet repeat stability.
@nl
prefLabel
Saccharomyces cerevisiae flap ...... ntain triplet repeat stability
@en
Saccharomyces cerevisiae flap ...... tain triplet repeat stability.
@nl
P2093
P2860
P1476
Saccharomyces cerevisiae flap ...... ntain triplet repeat stability
@en
P2093
Catherine H Freudenreich
Haihua Zhang
Janaki Veeraraghavan
Robert A Bambara
P2860
P304
P356
10.1128/MCB.24.9.4049-4064.2004
P407
P577
2004-05-01T00:00:00Z