about
P-Rex2, a new guanine-nucleotide exchange factor for RacHem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxisThe Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migrationPTEN function: how normal cells control it and tumour cells lose itRac GTPase signaling through the PP5 protein phosphatasePI3K and AKT: Unfaithful Partners in CancerPhosphoinositides: tiny lipids with giant impact on cell regulationHow cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motilityComputational analysis of the spatiotemporal coordination of polarized PI3K and Rac1 activities in micro-patterned live cellsSignaling by the phosphoinositide 3-kinase family in immune cellsRapid signaling at the plasma membrane by a nuclear receptor for thyroid hormoneAlsin is a Rab5 and Rac1 guanine nucleotide exchange factorProstaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocationChronophin coordinates cell leading edge dynamics by controlling active cofilin levelsInsulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cellsThe novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cellsPhosphoinositide 3-kinase p85beta regulates invadopodium formation.The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase.Role of phosphoinositide 3-kinase regulatory isoforms in development and actin rearrangementAdhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.Focal adhesion kinase as a regulator of cell tension in the progression of cancer.Integrin-mediated protein kinase A activation at the leading edge of migrating cells.Invasion of endothelial cells by tissue-invasive M3 type group A streptococci requires Src kinase and activation of Rac1 by a phosphatidylinositol 3-kinase-independent mechanism.ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasionThe distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migrationSingle-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signalingDifferential growth factor regulation of aspartyl-(asparaginyl)-beta-hydroxylase family genes in SH-Sy5y human neuroblastoma cells.RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms.HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway.The unique N-terminus of R-ras is required for Rac activation and precise regulation of cell migration.Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.Directed migration of cancer cells guided by the graded texture of the underlying matrix.Reconstitution and molecular analysis of an active human immunodeficiency virus type 1 Nef/p21-activated kinase 2 complex.Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1-PI3K-Rac1 pathway.p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppressionModelling cell polarization driven by synthetic spatially graded Rac activationDistinguishing modes of eukaryotic gradient sensing.Induction of nonapoptotic cell death by activated Ras requires inverse regulation of Rac1 and Arf6
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Phosphoinositide 3-kinase-dependent activation of Rac.
@ast
Phosphoinositide 3-kinase-dependent activation of Rac.
@en
type
label
Phosphoinositide 3-kinase-dependent activation of Rac.
@ast
Phosphoinositide 3-kinase-dependent activation of Rac.
@en
prefLabel
Phosphoinositide 3-kinase-dependent activation of Rac.
@ast
Phosphoinositide 3-kinase-dependent activation of Rac.
@en
P2093
P1433
P1476
Phosphoinositide 3-kinase-dependent activation of Rac.
@en
P2093
Len R Stephens
Phillip T Hawkins
W John Coadwell
P356
10.1016/S0014-5793(03)00454-X
P407
P50
P577
2003-07-01T00:00:00Z